259857-60-8

Basic information

• Product Name: methyl (R)-3-{[(tert-butoxycarbonyl)amino]methyl}-5-methylhexanoate
• CAS NO: 259857-60-8
• Molecular Weight: 273.373
• Mol File: 259857-60-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (R)-3-{[(tert-butoxycarbonyl)amino]methyl}-5-methylhexanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (R)-3-{[(tert-butoxycarbonyl)amino]methyl}-5-methylhexanoate(259857-60-8)
• EPA Substance Registry System: methyl (R)-3-{[(tert-butoxycarbonyl)amino]methyl}-5-methylhexanoate(259857-60-8)

Safety Data

• Hazardous Substances Data: 259857-60-8(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 259857-54-0 tert-butyl (S)-4-isobutyl-2-oxopyrrolidine-1-carboxylate 
• 34209-90-0 (E)-4-methyl-1-nitro-1-pentene 
• 1613627-31-8 (3,5-bis(trifluoromethyl)phenyl)(2-isobutylaziridin-1-yl)methanone 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1613627-71-6 (R)-methyl 3-((3,5-bis(trifluoromethyl)benzamido)methyl)-5-methylhexanoate 
• 1613627-47-6 (R)-dimethyl 2-(1-(3,5-bis(trifluoromethyl)benzamido)-4-methylpentan-2-yl)malonate 
• 259857-40-4 (S)-4-isopropyl-3-[(R)-5-methyl-3-(nitromethyl)hexanoyl]-5,5-diphenyloxazolidin-2-one 
• 181289-22-5 (R)-(+)-4-isobutyl-2-pyrrolidinone 

Relevant articles and documents

Regiodivergent kinetic resolution of terminal and internal rac -aziridines with malonates under dinuclear schiff base catalysis

Regiodivergent parallel kinetic resolution of aziridines with malonates was achieved under dinuclear Schiff base catalysis. The regiodivergent reaction proceeded under catalyst-control irrespective of the substituents on the aziridines, and 2.5-10 mol % of a Y(OTf)3/La(OiPr)3/a dinucleating Schiff base = 1:1:1 mixture gave versatile γ-amino acid derivatives in 96 → >99.5% ee. Not only terminal but also internal racemic aziridines reacted smoothly under suitably combined Lewis acid/Br?nsted base catalysis.