259867-08-8

Basic information

• Product Name: 1-[2-(2-{2-{2-[2-(2-benzyloxycarbonylamino-acetylamino)-3-methyl-butyrylamino]-acetylamino}-3-hydroxy-3-[4-methoxy-3-(3-methyl-butyl)-phenyl]-propionylamino}-acetylamino)-3-(1H-indol-3-yl)-propionyl]-pyrrolidine-2-carboxylic acid benzyl ester
• CAS NO: 259867-08-8
• Molecular Weight: 1059.23
• Mol File: 259867-08-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[2-(2-{2-{2-[2-(2-benzyloxycarbonylamino-acetylamino)-3-methyl-butyrylamino]-acetylamino}-3-hydroxy-3-[4-methoxy-3-(3-methyl-butyl)-phenyl]-propionylamino}-acetylamino)-3-(1H-indol-3-yl)-propionyl]-pyrrolidine-2-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(2-{2-{2-[2-(2-benzyloxycarbonylamino-acetylamino)-3-methyl-butyrylamino]-acetylamino}-3-hydroxy-3-[4-methoxy-3-(3-methyl-butyl)-phenyl]-propionylamino}-acetylamino)-3-(1H-indol-3-yl)-propionyl]-pyrrolidine-2-carboxylic acid benzyl ester(259867-08-8)
• EPA Substance Registry System: 1-[2-(2-{2-{2-[2-(2-benzyloxycarbonylamino-acetylamino)-3-methyl-butyrylamino]-acetylamino}-3-hydroxy-3-[4-methoxy-3-(3-methyl-butyl)-phenyl]-propionylamino}-acetylamino)-3-(1H-indol-3-yl)-propionyl]-pyrrolidine-2-carboxylic acid benzyl ester(259867-08-8)

Safety Data

• Hazardous Substances Data: 259867-08-8(Hazardous Substances Data)

Upstream product

• 259867-06-6 (2S,3S)-2-{2-[(S)-2-(2-Benzyloxycarbonylamino-acetylamino)-3-methyl-butyrylamino]-acetylamino}-3-hydroxy-3-[4-methoxy-3-(3-methyl-butyl)-phenyl]-propionic acid methyl ester 
• 259866-97-2 (S)-((2S,5R)-5-Isopropyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-yl)-[4-methoxy-3-(3-methyl-but-2-enyl)-phenyl]-methanol 
• 259867-04-4 (2S,3S)-2-Amino-3-hydroxy-3-[4-methoxy-3-(3-methyl-but-2-enyl)-phenyl]-propionic acid methyl ester 
• 187400-01-7 4-Bromo-1-methoxy-2-(3-methyl-but-2-enyl)-benzene 
• 870-63-3 prenyl bromide 
• 151071-00-0 4-bromo-2-(3-methylbut-2-en-1-yl)phenol 
• 56074-98-7 4-Methoxy-3-(γ,γ-dimethylallyl)benzaldehyde 
• 106-41-2 4-bromo-phenol 

Relevant articles and documents

Synthesis of the cyclic heptapeptide Substance P antagonist, dihydro-WIN67689 and determination of the stereochemistry of the modified tyrosine moiety

The total synthesis of semi-synthetic cyclic heptapeptide dihydro-WIN67689, a Substance P antagonist 70 times more potent than the naturally occurring cyclic peptide WIN66306, established the stereochemistry of the β-OH group in the isoprenyltyrosine moiety in I-III as R.