26000-17-9

Basic information

• Product Name: lycoctonine
• Synonyms: (16S)-20-Ethyl-4-(hydroxymethyl)-1α,6β,14α,16-tetramethoxyaconitane-7,8-diol
• CAS NO: 26000-17-9
• Molecular Formula: C₂₅H₄₁NO₇
• Molecular Weight: 467.599
• Product Categories: Alkaloids
• Mol File: 26000-17-9.mol
• Article Data: 6

Chemical Properties

• Melting Point: 143°
• Boiling Point: 570.07°C (rough estimate)
• Flash Point: 303.8°C
• Appearance: /
• Density: 1.1756 (rough estimate)
• Vapor Pressure: 8.31E-16mmHg at 25°C
• Refractive Index: 1.6000 (estimate)
• PKA: 12.30±0.70(Predicted)
• CAS DataBase Reference: lycoctonine(CAS DataBase Reference)
• NIST Chemistry Reference: lycoctonine(26000-17-9)
• EPA Substance Registry System: lycoctonine(26000-17-9)

Safety Data

• Hazardous Substances Data: 26000-17-9(Hazardous Substances Data)

Usage

General Description

Lycoctonine is a chemical compound found in various plant species, including the Lycopodium family of mosses and certain members of the Papaveraceae family of flowering plants. It is a type of alkaloid and has been found to possess strong anti-inflammatory and analgesic properties. Additionally, lycoctonine has shown potential as a natural remedy for treating various ailments, including arthritis, rheumatism, and other inflammatory conditions. Its biological activity and potential medicinal uses have attracted considerable interest from researchers and scientists. Further studies on lycoctonine may lead to the development of new pharmaceuticals and natural remedies for treating inflammation-related diseases and conditions.

InChI:InChI=1/C25H41NO7/c1-6-26-11-22(12-27)8-7-16(31-3)24-14-9-13-15(30-2)10-23(28,17(14)18(13)32-4)25(29,21(24)26)20(33-5)19(22)24/h13-21,27-29H,6-12H2,1-5H3/t13-,14-,15+,16+,17-,18+,19-,20+,21?,22+,23-,24+,25-/m1/s1

Upstream product

• 21019-30-7 [3H]-methyllycaconitine 
• 118225-75-5 C₃₈H₅₄N₂O₁₁ 
• 143423-45-4 lycoctonine triacetate 
• 21019-30-7 methyllycaconitine 

Downstream Products

• 1164101-67-0 anthranoyllycoctonine 
• 22413-78-1 anthranoyllycoctonine 
• 25488-62-4 delphatine 
• 129760-16-3 18-o-anisoyllycoctonine 
• 129760-15-2 18-p-anisoyllycoctonine 
• 129760-18-5 18-(3,4,5-trimethoxybenzoyl)lycoctonine 
• 129760-22-1 lycoctonine 18-O-p-phenyl-benzyl ether 

Relevant articles and documents

REACTIONS OF LYCOCTONINE ALKALOIDS WITH ACETIC ANHYDRIDE AND p-TOLUENESULFONIC ACID

The reactions of alkaloids having a 7,8-diol system - lycoctonine, browniine, and dihydromonticoline - with acetic anhydride and p-toluenesulfonic acid have been studied.The optimum conditions for this reaction, leading to anhydro compounds, have been found.

Covalent attachment of antagonists to the α7 nicotinic acetylcholine receptor: Synthesis and reactivity of substituted maleimides

The 3-methylmaleimide congeners of the natural product methyllycaconitine (MLA) and an analogue covalently attach to functional cysteine mutants of the α7 nicotinic acetylcholine receptor (nAChR).

Rapid and Efficient Isolation of the Nicotinic Receptor Antagonist Methyllycaconitine from Delphinium: Assignment of the Methylsuccinimide Absolute Stereochemistry as S

Methyllycaconitine (MLA) has been isolated from Garden Hybrid Delphinium and purified by vacuum liquid chromatography. 13C NMR and optical rotation has been used to characterize the absolute configuration of the methylsuccinimide moiety as S.Ligand binding assays confirmed the potency of MLA and its selectivity for α-bungarotoxin-sensitive neuronal nicotinic acetylcholine receptors.