21019-30-7 Usage
Biological Activity
Potent antagonist for α 7-containing neuronal nicotinic receptors (K i = 1.4 nM). Interacts with α 4 β 2 and α 6 β 2 receptors at concentrations > 40 nM. Attenuates METH-induced neurotoxicity in mouse striatum in vivo .
Check Digit Verification of cas no
The CAS Registry Mumber 21019-30-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,0,1 and 9 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 21019-30:
(7*2)+(6*1)+(5*0)+(4*1)+(3*9)+(2*3)+(1*0)=57
57 % 10 = 7
So 21019-30-7 is a valid CAS Registry Number.
InChI:InChI=1/C37H50N2O10/c1-7-38-17-34(18-49-32(42)20-10-8-9-11-23(20)39-26(40)14-19(2)31(39)41)13-12-25(46-4)36-22-15-21-24(45-3)16-35(43,27(22)28(21)47-5)37(44,33(36)38)30(48-6)29(34)36/h8-11,19,21-22,24-25,27-30,33,43-44H,7,12-18H2,1-6H3/t19?,21?,22-,24+,25?,27-,28?,29-,30+,33+,34+,35-,36?,37+/m1/s1
21019-30-7Relevant articles and documents
THE NATURAL OCCURRENCE AND PARTIAL SYNTHESIS OF 1α,4(S),6β,14α,16β-19,20-DIDEHYDRO-1,6,14,16-TETRAMETHOXY-4-OXY>METHYL>ACONITANE-7,8-DIOL; CONCERNING ANHWEIDELPHININE
Sun, Fang,Bai, Yili,Benn, Michael
, p. 1137 - 1141 (2007/10/02)
The title compound, alkaloid-Y, which is probably identical with anhweidelphinine, was isolated from Delphinium nuttalianum and its structure was proven by its conversion into methyllycaconitine, and also by its preparation from that alkaloid.