26031-63-0Relevant articles and documents
Anti-tubercular activity and molecular docking studies of indolizine derivatives targeting mycobacterial InhA enzyme
Venugopala, Katharigatta N.,Chandrashekharappa, Sandeep,Deb, Pran Kishore,Tratrat, Christophe,Pillay, Melendhran,Chopra, Deepak,Al-Shar’i, Nizar A.,Hourani, Wafa,Dahabiyeh, Lina A.,Borah, Pobitra,Nagdeve, Rahul D.,Nayak, Susanta K.,Padmashali, Basavaraj,Morsy, Mohamed A.,Aldhubiab, Bandar E.,Attimarad, Mahesh,Nair, Anroop B.,Sreeharsha, Nagaraja,Haroun, Michelyne,Shashikanth, Sheena,Mohanlall, Viresh,Mailavaram, Raghuprasad
, p. 1472 - 1487 (2021/07/10)
A series of 1,2,3-trisubstituted indolizines (2a–2f, 3a–3d, and 4a–4c) were screened for in?vitro whole-cell anti-tubercular activity against the susceptible H37Rv and multidrug-resistant (MDR) Mycobacterium tuberculosis (MTB) strains. Compounds 2b–2d, 3a
Base-mediated 1,3-dipolar cycloaddition of pyridinium bromides with bromoallyl sulfones: a facile access to indolizine scaffolds
Ganga Reddy, Velma,Hari Krishna, Namballa,Jadala, Chetna,Kamal, Ahmed,Shankaraiah, Nagula
, p. 8694 - 8701 (2020/11/17)
An expedient and transition-metal-free synthetic strategy has been developed for the construction of substituted indolizines from a unique combination of pyridinium salts and 2-bromoallyl sulfones. This approach does not compromise with the diverse substitutions on both the pyridinium salts and 2-bromoallyl sulfones. Wide substrate scope, operational simplicity, milder reaction conditions and good to moderate yields are the merits associated with the current approach. Moreover, this method provides two products which are amenable for the generation of a library of key indolizine building blocks. This journal is
Greener synthesis of indolizine analogues using water as a base and solvent: study for larvicidal activity against Anopheles arabiensis
Sandeep, Chandrashekharappa,Venugopala, Katharigatta N.,Gleiser, Raquel M.,Chetram, Abeen,Padmashali, Basavaraj,Kulkarni, Rashmi S.,Venugopala, Rashmi,Odhav, Bharti
, p. 899 - 904 (2016/11/11)
Greener synthesis of a series of novel indolizine analogues have been achieved by the cyclization of aromatic cycloimmonium ylides with electron-deficient alkynes in the presence of water as the base and solvent at 80?°C. Yield of the title compounds was