260353-11-5

Basic information

• Product Name: 3(2H)-Pyridazinone,6-[1,1'-biphenyl]-4-yl-4-(4,5-dihydro-5-oxo-1,3-diphenyl-1H-pyrazol-4-yl)-4,5-dihydro-
• CAS NO: 260353-11-5
• Molecular Formula: C31H24N4O2
• Molecular Weight: 484.557
• Mol File: 260353-11-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3(2H)-Pyridazinone,6-[1,1'-biphenyl]-4-yl-4-(4,5-dihydro-5-oxo-1,3-diphenyl-1H-pyrazol-4-yl)-4,5-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-Pyridazinone,6-[1,1'-biphenyl]-4-yl-4-(4,5-dihydro-5-oxo-1,3-diphenyl-1H-pyrazol-4-yl)-4,5-dihydro-(260353-11-5)
• EPA Substance Registry System: 3(2H)-Pyridazinone,6-[1,1'-biphenyl]-4-yl-4-(4,5-dihydro-5-oxo-1,3-diphenyl-1H-pyrazol-4-yl)-4,5-dihydro-(260353-11-5)

Safety Data

• Hazardous Substances Data: 260353-11-5(Hazardous Substances Data)

Upstream product

• 4845-49-2 1,3-diphenyl-5-oxo-4,5-dihydro-1H-pyrazole 

Downstream Products

• 377047-49-9 6-biphenyl-3-chloropyridazine 
• 88490-32-8 (6-biphenyl-4-yl-pyridazin-3-yl)-hydrazine 

Relevant articles and documents

Some reactions with 6-(biphenyl)-4-(5-oxo-1,3-diphenyl-2-pyrazolin-4-yl)-4,5-dihydropyridazin-3-(2H) ones

4-biphenyl-4-oxo-2-butenoic acid (1) reacted with 1,3-diphenyl-2-pyrazolin-5-one (2) to give 4-biphenyl-4-oxo-2-(5-oxo-1,3-diphenyl-2-pyrazolin-4-yl) butanoic acid (3) The condensation of (3) with hydrazines affords the corresponding pyridazinones (4, 5). Reaction of pyridazinone (4) with POCl3 gave the chloropyridazine derevative (7) which was subjected to further studies with hydrazine hydrate, aromatic amines, anthranilic acid, thiourea and sulfa drugs to give compounds (8-15). Reaction of pyridazinone (4) with phosphorus pentasulfide gave the corresponding thiopyridazine derivative (16). The in-vitro antibacterial screening revealed that some of the new compounds possess activity against Gram-positive, Gram-negative bacteria and fungi.