260353-65-9Relevant academic research and scientific papers
PRODRUGS OF EXCITATORY AMINO ACIDS
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Example 8.e, (2010/11/30)
This invention relates to a synthetic excitatory amino acid prodrug and processes for its preparation. The invention further relates to methods of using, and pharmaceutical compositions comprising, the compounds for the treatment of neurological disorders and psychiatric disorders.
PRODRUGS OF EXCITATORY AMINO ACIDS
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Page 89, (2008/06/13)
This invention relates to synthetic excitatory amino acid prodrugs and processes for their preparation. The invention further relates to methods of using, and pharmaceutical compositions comprising, the compounds for the treatment of neurological disorder
6-fluorobicyclo[3.1.0]hexane derivatives
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, (2008/06/13)
The present invention provides fluorobicyclo[3.1.0]hexane derivatives represented by the formula [wherein R1and R2are the same or different and each represents a hydrogen atom, a C1-10alkyl group, a C3-8cycloalk
Synthesis, SARs, and pharmacological characterization of 2-Amino-3 or 6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent, selective, and orally active group II metabotropic glutamate receptor agonists
Nakazato,Kumagai,Sakagami,Yoshikawa,Suzuki,Chaki,Ito,Taguchi,Nakanishi,Okuyama
, p. 4893 - 4909 (2007/10/03)
(+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (4, LY354740), a highly selective and orally active group II metabotropic glutamate receptor (mGluR) agonist, has increased interest in the study of group II mGluRs. Our interest focused on a conformat
