260441-12-1

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 2252-63-3 1-(4-Fluorophenyl)piperazine 

Downstream Products

• 260441-13-2 1-(4-fluorophenyl)-4-(trans-β-styrenesulfonyl)piperazine 
• 260441-33-6 1-(6-chloro-2-hexanone-1-sulfonyl)-4-(4-fluorophenyl)piperazine 
• 312759-84-5 4-(4-fluorophenyl)-1-[2-(1-t-butoxycarbonylpiperidin-4-yl)ethenylsulphonyl]piperazine 
• 895573-82-7 diethyl({[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}methyl)phosphonate 

Relevant academic research and scientific papers

SULFONYL AMINO CYCLIC DERIVATIVES AND USE THEREOF

The present invention is related to derivatives of Formula (I) and use thereof in particular for the treatment and/or prophylaxis of autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, cancer, respiratory diseases and fibrosis, including multiple sclerosis, arthritis, emphysema, chronic obstructive pulmonary disease, liver and pulmonary fibrosis.

Arylpiperazines and their use as metalloproteinase inhibiting agents (MMP)

Arylpiperazines of formula (I) useful as metalloproteinase inhibitors, especially as inhibitors of MMP 13.

Arylpiperazines and arylpiperidines and their use as metalloproteinase inhibiting agents

Compounds of formula (I) useful as metalloproteinase inhibitors, especially as inhibitors of MMP 13.