260441-44-9

Basic information

• Product Name: 2-(PIPERIDIN-4-YL-OXY)-5-CHLOROPYRIDINE
• Synonyms: 5-CHLORO-2-(PIPERIDIN-4-YLOXY)-PYRIDINE;2-(PIPERIDIN-4-YL-OXY)-5-CHLOROPYRIDINE
• CAS NO: 260441-44-9
• Molecular Formula: C10H13ClN2O
• Molecular Weight: 212.68
• Mol File: 260441-44-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 304.7°C at 760 mmHg
• Flash Point: 138.1°C
• Appearance: /
• Density: 1.2g/cm³
• Vapor Pressure: 0.000861mmHg at 25°C
• Refractive Index: 1.541
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(PIPERIDIN-4-YL-OXY)-5-CHLOROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(PIPERIDIN-4-YL-OXY)-5-CHLOROPYRIDINE(260441-44-9)
• EPA Substance Registry System: 2-(PIPERIDIN-4-YL-OXY)-5-CHLOROPYRIDINE(260441-44-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 260441-44-9(Hazardous Substances Data)

Usage

General Description

2-(Piperidin-4-yl-oxy)-5-chloropyridine is a synthetic chemical compound that belongs to the category of organic compounds known as diarylethers. It is classified under pyridine and piperidine alkaloids. This specific compound has a piperidinyl group (a nitrogenous ring structure) combined with a chloropyridine moiety, which is a six-membered heterocyclic aromatic ring system that contains a chlorine atom. The ether linkage is characterized by an oxygen atom connecting the two ring systems. The properties and potential applications of this compound may depend on its reactivity with other substances, and it is relevant in chemical research. However, detailed research concerning its uses and effects is limited. Like other chemicals, careful handling, storage, and disposal are necessary.

InChI:InChI=1/C10H13ClN2O/c11-8-1-2-10(13-7-8)14-9-3-5-12-6-4-9/h1-2,7,9,12H,3-6H2

Upstream product

• 16110-09-1 2,5 dichloropyridine 
• 950672-31-8 5-chloro-2-(piperidin-4-yloxy)-pyridine acetate 
• 5382-16-1 4-HYDROXYPIPERIDINE 

Downstream Products

• 459814-89-2 (5S)-5-[4-(5-chloropyridin-2-yloxy)piperidine-1-sulfonylmethyl]-5-methylimidazolidine-2,4-dione 

Relevant articles and documents

NOVEL CRYSTAL MODIFICATIONS

Novel crystal modifications of (5S)-5-[4-(5-chloro-pyridin-2-yloxy)-piperidine-1-sulfonylmethyl]-5-methyl-imidazolidine-2,4-dione are disclosed together with processes for preparing such modifications, pharmaceutical compositions comprising such a modification, and the use of such a modification in therapy.

NOVEL AZA-RING DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS

This invention relates to novel aza-dng dedvatives useful as monoamine neurotransmifter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Compounds

Compounds of the formula I useful as metalloproteinase inhibitors, especially as inhibitors of MMP 13.