260447-12-9

Basic information

• Product Name: C₂₂H₁₈O₃
• Synonyms: C₂₂H₁₈O₃
• CAS NO: 260447-12-9
• Molecular Weight: 330.383
• Mol File: 260447-12-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₂₂H₁₈O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₁₈O₃(260447-12-9)
• EPA Substance Registry System: C₂₂H₁₈O₃(260447-12-9)

Safety Data

• Hazardous Substances Data: 260447-12-9(Hazardous Substances Data)

Upstream product

• 90-02-8 salicylaldehyde 
• 100-44-7 benzyl chloride 
• 118-93-4 o-hydroxyacetophenone 
• 5896-17-3 2-(phenylmethoxy)benzaldehyde 

Downstream Products

• 1209470-26-7 3-benzyl-2,2'-dihydroxychalcone 
• 105827-34-7 2-(2-hydroxyphenyl)-3-methoxy-4H-chromen-4-one 
• 6068-76-4 3,2'-dihydroxyflavone 

Relevant articles and documents

Metal-free Synthesis of Spiro-2,2′-benzo[b]furan-3,3′-ones via PhI(OAc)2-Mediated Cascade Spirocyclization

Treating the benzyl protected 3-hydroxy-1,3-bis(2-hydroxyphenyl)prop-2-en-1-ones solely with PhI(OAc)2 (PIDA) in DCE at room temperature readily furnished the seldom studied spiro-2,2′-benzo[b]furan-3,3′-ones in satisfactory to excellent yields. The hypervalent iodine reagent enables the metal-free cascade spirocyclization resulting in the dual oxidative C?O bond formation. (Figure presented.).

Acidic rearrangement of (benzyloxy)chalcones: A short synthesis of chamanetin

Treatment of (benzyloxy)chalcones with trifluoroacetic acid in refluxing chloroform gave several new benzyl(hydroxy)flavanones in high yields and good regioselectivities. By using this procedure, we prepared the natural compound chamanetin in good yield from readily available reagents. Georg Thieme Verlag Stuttgart - New York.