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Usage

Uses

Used in Biotechnology Industry:
3,2'-Dihydroxyflavone is used as a method for increasing the isolation efficiency and autologous proliferation of urine-derived stem cells. This application is particularly relevant in the field of regenerative medicine, where stem cells are used to repair or replace damaged tissues and organs. The use of 3,2'-dihydroxyflavone in this context can potentially improve the yield and quality of stem cells obtained from urine, making the process more efficient and cost-effective.

Upstream product

• 15131-80-3 trans-2,2'-dihydroxychalcone 
• 29219-03-2 3-hydroxy-2-(2-methoxy-phenyl)-chromen-4-one 
• 42220-77-9 (2E)-1-(2-hydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one 
• 118-93-4 o-hydroxyacetophenone 
• 135-02-4 ortho-anisaldehyde 
• 90-02-8 salicylaldehyde 
• 34000-30-1 2',2-dihydroxychalcone 
• 5896-17-3 2-(phenylmethoxy)benzaldehyde 
• 260447-12-9 C₂₂H₁₈O₃ 

Downstream Products

• 105827-34-7 2-(2-hydroxyphenyl)-3-methoxy-4H-chromen-4-one 

Relevant academic research and scientific papers

Phototransformations of some 3-cyclohexenyloxychromenones: Synthesis of Spirocyclic compounds

The phototransformation of the 3-cyclohexenyloxychromenones by irradiation with a pyrex-filtered light from a 125 W Hg vapor lamp under an inert atmosphere into the spirocyclic fused xanthenones was described. The efficacy of the protocol depended upon th

3′-Hydroxy-3,4′-dimethoxyflavone blocks tubulin polymerization and is a potent apoptotic inducer in human SK-MEL-1 melanoma cells

Flavonoids are naturally occurring polyphenolic compounds and are among the most promising anticancer agents. A series of flavonols and their 3-methyl ether derivatives were synthesized and assessed for cytotoxicity. It was found that 3′-hydroxy-3,4′-dime

Synthesis, antimicrobial activity and molecular docking of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized oxygen heterocycles

A convenient approach for the synthesis of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized heterocyclic rings (eight-, nine-, ten- and eleven-membered rings) containing two oxygen atoms from flavonols through alkylation using different dibromoalkanes was described. The synthesized compounds were established based on the spectral data and X-ray crystal structure for 6c. The synthesized compounds were evaluated for their in vitro antimicrobial activity. Docking studies were carried out for most active two compounds 6f and 6i.

Effect of flavonol derivatives on the carrageenin-induced paw edema in the rat and inhibition of cyclooxygenase-1 and 5-lipoxygenase in vitro.

Alkoxyflavonols were synthesized by the Algar-Flynn-Oyamada (AFO) cyclization of chalcones. Hydroxyflavonols were prepared by dealkylation of methoxyflavonols by refluxing in hydroiodic acid. The alkoxyflavonols 3-hydroxy-2-(2,3,4-trimethoxyphenyl)-4H-chr