2606-91-9Relevant academic research and scientific papers
Isoselective Lactide Ring Opening Polymerisation using [2]Rotaxane Catalysts
Lim, Jason Y. C.,Yuntawattana, Nattawut,Beer, Paul D.,Williams, Charlotte K.
supporting information, p. 6007 - 6011 (2019/04/03)
Polylactide (PLA) is a fully biodegradable and recyclable plastic, produced from a bio-derived monomer: it is a circular economy plastic. Its properties depend upon its stereochemistry and isotactic PLA shows superior thermal-mechanical performances. Here, a new means to control tacticity by exploiting rotaxane conformational dynamism is described. Dynamic achiral [2]rotaxanes can show high isoselectivity (Pi=0.8, 298 K) without requiring any chiral additives and enchain by a chain end control mechanism. The organocatalytic dynamic stereoselectivity is likely applicable to other small-molecule and polymerization catalyses.
Reliable and general method for the cleavage of α-arylheteroatom- substituted carboxylic acids
Spurg, Anke,Waldvogel, Siegfried R.
, p. 3042 - 3044 (2008/03/12)
Bonds between arylheteroatom moieties and α-carbons of carboxylic acids are efficiently cleft by azide transfer and subsequent Curtius rearrangement. The scope of the one-pot protocol covers differently substituted carboxylic acids and heteroatoms like O, S, Se, and N. Georg Thieme Verlag Stuttgart.
2-ARYLTHIAZOLE DERIVATIVES AS CXCR3 RECEPTOR MODULATORS
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Page/Page column 64, (2010/11/28)
The invention encompasses compounds of Formula I or pharmaceutically acceptable salts thereof, which are modulators of the CXCR3 chemokine receptor function useful for the treatment or prevention of pathogenic inflammatory processes, autoimmune diseases or graft rejection processes. Methods of use and pharmaceutical compositions are also encompassed.
