26061-11-0

Upstream product

• 50903-99-6 L-NAME 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 3674-06-4 Boc-Phe-ONSu 
• 51298-62-5 _N^ω-nitro-L-arginine methyl ester hydrochloride 

Downstream Products

• 50573-05-2 Phe-Arg(NO₂)-OH 
• 17461-58-4 Boc-L-Phe-L-Arg^NO₂ 
• 82308-66-5 (S)-2-{(S)-2-[((S)-1-Acetyl-pyrrolidine-2-carbonyl)-amino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid methyl ester; hydrochloride 
• 82308-64-3 (S)-2-[(S)-2-(2-Acetylamino-acetylamino)-3-phenyl-propionylamino]-5-guanidino-pentanoic acid methyl ester; hydrochloride 
• 82308-63-2 (S)-2-((S)-2-Acetylamino-3-phenyl-propionylamino)-5-guanidino-pentanoic acid methyl ester; hydrochloride 
• 85917-92-6 C₂₃H₃₃N₇O₇ 
• 85917-96-0 C₂₀H₂₉N₇O₇ 
• 85917-91-5 C₁₈H₂₆N₆O₆ 
• 75816-30-7 C₁₆H₂₄N₆O₅*ClH 
• 17461-58-4 Boc-Phe-Arg(NO₂)-OH 
• 47556-24-1 Phe-Arg(NO₂)-OCH₃ 

Relevant academic research and scientific papers

Selective inhibition of neuronal nitric oxide synthase by N(ω)- nitroarginine- and phenylalanine-containing dipeptides and dipeptide esters

A series of N(ω)-nitroarginine (Arg(NO2))- and phenylalanine- containing dipeptides and dipeptide esters were synthesized as potential selective inhibitors of neuronal nitric oxide synthase (nNOS). All of the dipeptides and dipeptide esters are

Synthesis and biological activity of acylated and telomerized peptides as potential HIV-fixation inhibitors

In order to inhibit the gp 120-CD4 glycoprotein interaction, a key step of the HIV-infection, we have synthesized a series of N-acylated peptides containing sequences identified in both the viral and lymphocytic proteins, (SDFR, SDAR, RFDSAARFDS, DRADSRRS, PSKLNDRADSRRSLWD, ASTTTNYT). An hydrophobic moiety (capryloyl, palmitoyl acrylamidoundecanoyl) was introduced in the last step of interative synthesis, in homogeneous or solid phase. The acryloyl-containing compounds were then telomerized under UV irradiation (DPn observed: 2 to 6). The biological evaluation shown an antiviral effect in vitro for telomerized peptides containing amino diacids such as Glu and Asp.

A RAPID AND EFFICIENT SYNTHETIC ROUTE TO BIOLOGICALLY IMPORTANT L-ARGININE PEPTIDES

A modified synthetic route for the preparation of Nα-acetylated peptide methyl esters has been developed.This technique was successfully employed for the synthesis of seven extended Nα-acetyl-L-arginine methyl esters.