50903-99-6

Basic information

• Product Name: NG-Nitroarginine Methyl Ester
• Synonyms: NG-Nitroarginine Methyl Ester;N5-[Imino(nitroamino)methyl]-L-ornithine methyl ester;NG-Nitroarginine methyl;η-Nitroarginine methyl;η-Nitro-L-arginine methyl;ω-Nitroarginine methyl;L-Ornithine, N5-[iMino(nitroaMino)Methyl]-, Methyl ester
• CAS NO: 50903-99-6
• Molecular Formula: C₇H₁₅N₅O₄
• Molecular Weight: 233.2251
• Mol File: 50903-99-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 375.47°C (rough estimate)
• Flash Point: 185.8°C
• Appearance: /
• Density: 1.3521 (rough estimate)
• Vapor Pressure: 4.37E-06mmHg at 25°C
• Refractive Index: 1.8000 (estimate)
• CAS DataBase Reference: NG-Nitroarginine Methyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: NG-Nitroarginine Methyl Ester(50903-99-6)
• EPA Substance Registry System: NG-Nitroarginine Methyl Ester(50903-99-6)

Safety Data

• Hazardous Substances Data: 50903-99-6(Hazardous Substances Data)

Usage

Definition

ChEBI: An alpha-amino acid ester that is the methyl ester of Ngamma-nitro-L-arginine.

InChI:InChI=1/C7H15N5O4/c1-16-6(13)5(8)3-2-4-10-7(9)11-12(14)15/h5H,2-4,8H2,1H3,(H3,9,10,11)/t5-/m0/s1

Upstream product

• 1119-34-2 L-arginine hydrochloride 
• 112208-06-7 N^α-(tert-butoxycarbonyl)-N^G-nitro-L-arginine methyl ester 
• 2188-18-3 Boc-Arg(NO₂)-OH 
• 67-56-1 methanol 
• 2149-70-4 N-nitro-L-arginine 

Downstream Products

• 106386-19-0 N^α-(N²,N⁶-bis-benzyloxycarbonyl-L-lysyl)-N^ω-nitro-L-arginine methyl ester 
• 66345-00-4 C₁₈H₂₆N₆O₇ 
• 23734-44-3 Cbo-L-Val-nitro-L-Arg-methylester 
• 106655-93-0 -(nitro-L-arginin-methylester) 
• 81666-53-7 Z-glycyl-N^G-nitro-L-arginine methyl ester 
• 16876-12-3 N-Benzyloxycarbonyl-(α-tert.butyl-γ-Glu)-(ω-N-nitro-Arg)-methylester 
• 5619-24-9 C₂₃H₃₄N₆O₉ 
• 2785-17-3 N^α-(N²-benzyloxycarbonyl-L-asparaginyl)-N^ω-nitro-L-arginine methyl ester 
• 1000072-69-4 methyl (2S)-5-(2-nitroguanidino)-2-((3-phenylaziridin-2-yl)methylamino)pentanoate 
• 64181-07-3 3β-hydroxy-lup-20(29)-en-30-al 
• 1207974-55-7 (S)-5-N(G)-nitro-guanidino-2-{[3-(4-nitro-benzenesulfonylamino)thiophene-2-carbonyl]amino}pentanoic acid methyl ester 
• 1186506-68-2 C₃₄H₄₇N₇O₉ 
• 406953-56-8 2-(S)-[2-(S)-(tert-butoxycarbonyl-methyl-amino)-3-phenyl-propionylamino]-5-nitroguanidino-pentanoic acid methyl ester 
• 406953-75-1 2-(S)-(2-benzyl-6-phenyl-hexanoylamino)-5-nitroguanidino-pentanoic acid methyl ester 

Relevant articles and documents

A class of novel Schiff's bases: Synthesis, therapeutic action for chronic pain, anti-inflammation and 3D QSAR analysis

To discover analgesics for treating chronic pain 17 novel Schiff's bases, N,N′-(Z-allylidene-1,3-diyl)bisamino acid methyl esters were prepared from 1,1,3,3,-tetramethoxypropane and amino acid methyl esters. On tail-flick mouse model 20 μmol/kg of these Schiff's bases were orally administered, the analgesic action started 30 min after administration, reached the maximum 120 min after administration, and at 180 min this action was still observed. On a xylene-induced ear edema mouse model 20 μmol/kg of these Schiff's bases exhibited desirable anti-inflammation. Thus the present Schiff's bases are able to treat chronic pain from inflammation. The effect of the side chains of the amino acid residues of these Schiff's bases on the analgesic activity was explained with 3D QSAR.