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5H-benzo[b]pyrido[3,2-e][1,4]oxazines are a class of heterocyclic compounds characterized by a unique fused ring structure, consisting of a benzene ring, a pyridine ring, and an oxazine ring. These compounds exhibit a wide range of biological activities, including antitumor, antiviral, and anti-inflammatory properties, making them of interest in the field of medicinal chemistry. The chemical structure of 5H-benzo[b]pyrido[3,2-e][1,4]oxazines is defined by the presence of a nitrogen atom in the pyridine ring and an oxygen atom in the oxazine ring, which contributes to their diverse pharmacological properties. Research on these compounds is ongoing, with the aim of developing new therapeutic agents and understanding their mechanisms of action.

261-82-5

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261-82-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 261-82-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,6 and 1 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 261-82:
(5*2)+(4*6)+(3*1)+(2*8)+(1*2)=55
55 % 10 = 5
So 261-82-5 is a valid CAS Registry Number.

261-82-5Downstream Products

261-82-5Relevant academic research and scientific papers

Base-regulated tunable synthesis of pyridobenzoxazepinones and pyridobenzoxazines

Shen, Chaoren,Wu, Xiao-Feng

, p. 4433 - 4443 (2015/09/01)

A base-regulated one-pot protocol for the tunable synthesis of pyridobenzoxazepinones and pyridobenzoxazines has been developed. The preparation of pyridobenzoxazepinones is achieved in moderate to good yield by utilizing an aromatic nucleophilic substitution (SNAr, O-arylation)/carbonylation tandem reaction. Mechanistic studies suggest that SNAr (O-arylation) proceeds prior to the aminocarbonylation. Through the regulation of bases, pyridobenzoxazines can be obtained via successive SNAr (O-arylation and then N-arylation). Base is crucial for the regulation of the products.

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