26103-49-1 Usage
Uses
Used in Pharmaceutical Industry:
3-(Piperidin-1-ylsulphonyl)pyridine is used as a building block in organic synthesis for the development of new pharmaceutical compounds. Its unique chemical structure allows for the creation of diverse drug candidates with potential therapeutic applications.
Used in Medicinal Chemistry Research:
PPS is used as a research tool to investigate its pharmacological properties, such as its ability to act as a serotonin receptor antagonist and to inhibit the enzyme poly(ADP-ribose) polymerase. These properties make it a valuable compound for studying the underlying mechanisms of various diseases and conditions.
Used in Cancer Treatment:
3-(Piperidin-1-ylsulphonyl)pyridine is used as a potential therapeutic agent in the treatment of cancer. Its pharmacological properties may contribute to the inhibition of tumor growth and the modulation of cancer-related signaling pathways, offering a new approach to cancer therapy.
Used in Inflammatory Disorder Management:
PPS is used as a potential treatment for inflammatory disorders due to its ability to modulate immune responses and reduce inflammation. This makes it a promising candidate for the development of new anti-inflammatory drugs.
Used in Neurodegenerative Disease Therapy:
3-(Piperidin-1-ylsulphonyl)pyridine is used as a potential therapeutic agent in the treatment of neurodegenerative diseases. Its pharmacological properties may help protect neurons from degeneration and support the development of new treatments for conditions such as Alzheimer's and Parkinson's disease.
Check Digit Verification of cas no
The CAS Registry Mumber 26103-49-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,1,0 and 3 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 26103-49:
(7*2)+(6*6)+(5*1)+(4*0)+(3*3)+(2*4)+(1*9)=81
81 % 10 = 1
So 26103-49-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2O2S/c13-15(14,10-5-4-6-11-9-10)12-7-2-1-3-8-12/h4-6,9H,1-3,7-8H2
26103-49-1Relevant academic research and scientific papers
Palladium-catalyzed sulfination of aryl and heteroaryl halides: Direct access to sulfones and sulfonamides
Shavnya, Andrei,Coffey, Steven B.,Smith, Aaron C.,Mascitti, Vincent
supporting information, p. 6226 - 6229 (2014/01/17)
A novel palladium-catalyzed sulfination of aryl and heteroaryl halides is described. This reaction operates under mild conditions and provides access to a wide range of aryl and heteroaryl sulfinates, a useful and versatile class of synthetic intermediates. Capitalizing on this sulfination reaction, one-pot protocols allowing direct access to sulfones and sulfonamides have also been developed. The practicality of these transformations is illustrated with the parallel synthesis of analogues of the drug Viagra.
A General and Efficient Synthesis of Sulfonylbenzotriazoles from N-Chlorobenzotriazole and Sulfinic Acid Salts
Katritzky, Alan R.,Rodriguez-Garcia, Valerie,Nair, Satheesh K.
, p. 1849 - 1852 (2007/10/03)
One-pot reactions of sulfinic acid salts (produced from organometallic reagents with SO2) with N-chlorobenzotriazole gave the corresponding N-alkane-, N-arene-, and N-heteroenesulfonylbenzotriazoles 3a-j in 41-93% yields. Reagents 3a-j are effi
