26113-25-7Relevant articles and documents
Design and surface/interfacial properties of asymmetric triazine carboxyl betaine surfactants
Jing, Lishuai,Qiao, Weihong,Luo, Limei,Peng, Huan
, p. 629 - 636 (2014)
The design, synthesis and interfacial behaviors of six asymmetric carboxyl betaine surfactants (BCm-n, m, n = 8, 10, 12, or 14, m ≠ n) derived from s-triazine, which were prepared from cyanuric chloride, aliphatic amines, N,N-dimethylpropane-1,3-diamine, followed by the reaction with sodium chloroacetate, are reported. The structures were confirmed by MS,1H NMR and FT-IR. Compared with symmetric surfactants (BCn-n, n = 8, 10, 12, or 14) we previously synthesized, the asymmetric series show superior surface activity. The γCMC of surfactants BC10-8, BC12-8, BC14-8 and BC12-10 is all below 30 mN/m. The minimum alkane carbon number of these ten surfactants is determined to be between 10 and 14. The interfacial behaviors between the alkanes and the solutions of triazine carboxyl betaine surfactants show that surfactants with a total carbon number in hydrophobic chains between 16 and 22 exhibit the ability to reduce the interfacial tension to an ultra-low value (10-3 mN/m). The surfactants with longer hydrocarbon chains display strong affinity to the alkanes with longer chains.
Efficient cell transfection with melamine-based gemini surfactants
Perrone, Serena,Usai, Michele,Lazzari, Paolo,Tucker, Steven J.,Wallace, Heather M.,Zanda, Matteo
, p. 176 - 187 (2013)
Gemini surfactants consisting of two melamine scaffolds connected by a n-hexyl linker and functionalized with a 1-propylammonium polar head and a lipophilic chain having variable carbon length (from C8 to C16) were synthesized. These were then used successfully for the transfection of A549, U87 MG, and Bristol 8 cell lines with maxGFP expressing plasmid. The transfection protocol was optimized appropriately (confluence, reagent/pcDNA ratio, compaction time, and transfection time) for each cell line. Under optimized conditions, the C12 and C14 melamine gemini surfactants showed little toxicity and remarkable transfection efficiency, superior to the gold-standard Lipofectamine 2000. These reagents were also able to efficiently transfect primary DRG neurons, which are notoriously difficult to transfect. The presence of serum completely inhibited the transfection capacity of these reagents. Owing to their ready availability, straightforward synthesis, high chemical stability (even in solution), ease of use (no formulation is required), improved transfection ability, and low toxicity, melamine-based gemini surfactants are very promising reagents for cellular DNA transfection.
Sustainable triazine-derived quaternary ammonium salts as antimicrobial agents
Morandini, Andrea,Spadati, Emanuele,Leonetti, Benedetta,Sole, Roberto,Gatto, Vanessa,Rizzolio, Flavio,Beghetto, Valentina
, p. 28092 - 28096 (2021)
The first examples of highly efficient antimicrobial triazine-derived bis imidazolium quaternary ammonium salts (TQAS) are reported. TQAS have been prepared with an easy, atom efficient, economically sustainable strategy and tested as antimicrobial agents
A reagent for analysis of blood and preparation method therof
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Paragraph 0074-0079, (2018/05/03)
The present invention relates to a compound for analysis of blood capable of replacing existing reagents for analysis of blood, and a preparation method thereof. A compound of the present invention can rapidly dissolve blood cells, thereby being applicable as a composition for dissolving blood cells. Also, the compound can be applied as a composition for analysis of blood, thereby being capable of replacing existing reagents (compositions) for analysis of blood and improving analysis efficiency. To this end, the compound is represented by chemical formula 1c or 1d.COPYRIGHT KIPO 2018
