26114-25-0

Basic information

• Product Name: Aziridine, 2,3-diphenyl-
• Synonyms: (2S,3S)-2,3-diphenylaziridine;(S,S)-2,3-diphenylaziridine;(S)-trans-2,3-diphenyl-aziridine;(S)-trans-2,3-Diphenyl-aziridin;cis-2,3-Diphenylaziridin;trans-2,3-Diphenylaziridin
• CAS NO: 26114-25-0
• Molecular Formula: C14H13N
• Molecular Weight: 195.264
• Mol File: 26114-25-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 309.0±11.0 °C(Predicted)
• Density: 1.099±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Aziridine, 2,3-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Aziridine, 2,3-diphenyl-(26114-25-0)
• EPA Substance Registry System: Aziridine, 2,3-diphenyl-(26114-25-0)

Safety Data

• Hazardous Substances Data: 26114-25-0(Hazardous Substances Data)

Upstream product

• 952-06-7 deoxybenzoin oxime 
• 49855-40-5 D-erythro-α'-chloro-bibenzylyl-(α)-amine 
• 183184-04-5 (R,R)-(+)-4,5-diphenyl-1,3,2-dioxathiolan-2-one 
• 52340-78-0 (R,R)-hydroxybenzoin 
• 1151538-49-6 trans-(2S,3S)-2-phenyl-3-[(S)-2-(p-toluenesulfinyl)phenyl]-1-[(R)-(p-toluenesulfinyl)]aziridine 
• 133522-22-2 (1R,2S)-2-azido-1,2-diphenylethan-1-ol 
• 588-59-0 stilbene 
• 23190-16-1 (1R,2S)-2-Amino-1,2-diphenylethanol 

Downstream Products

• 530-36-9 erythro-2-amino-1,2-diphenylethanol 
• 530-36-9 threo-1,2-diphenyl-2-aminoethan-1-ol 
• 49855-40-5 (+/-)-erythro-α'-chloro-bibenzylyl-(α)-amine 
• 1174415-69-0 3-chloro-6-(2,3-diphenylaziridin-1-yl)-s-tetrazine 

Relevant articles and documents

Chiral sulfide - phosphine ligand and preparation method and use thereof

The present invention provides a novel chiral thioether-phosphine ligand and a preparation method and application thereof. The ligand is a compound shown as a formula I, or enantiomer, non-enantiomer, racemate, pharmaceutically acceptable salt, hydrate and solvate crystal thereof. R1 is an optionally substituted phenyl, and optionally substituted naphthyl; and R2 is methyl and benzyl. The chiral thioether-phosphine ligand provided by the invention as a copper-catalyzed asymmetric cycloaddition ligand can be directly used to prepare various pyrrolidine compounds with substituted multiple chiral centers.

Enantioselective synthesis of tetrahydrofuran derivatives by sequential henry reaction and iodocyclization of γ,δ-unsaturated alcohols

A sequential one-pot Cu-catalyzed asymmetric Henry reaction and iodocyclization is disclosed. The transformation provides efficient access to biologically and synthetically useful 2,2,5-trisubstituted tetrahydrofuran derivatives. The combination of Cu(OAc)2·H2O with a novel chiral sulfoxide-Schiff base hybrid ligand under mild reaction conditions tolerates a wide range of 4-substituted γ,δ-unsaturated aldehydes, and the subsequent iodocyclization furnishes the corresponding products in generally high yields with excellent enantioselectivities. The products can be easily converted into amines with excellent diastereo- and enantioselectivities.

2-(p-Tolylsulfinyl)benzyl halides as efficient precursors of optically pure trans-2,3-Disubstituted aziridines

Aziridination of (R)-N-sulfinylaldimines (aryl, heteroaryl and alkenyl derivatives) with 2-(p-tolyl sulfinyl)benzyl iodide in the presence of sodium hexamethyl disilazide takes place with almost complete control of the stereoselectivity (facial and antil