2613-34-5

Basic information

• Product Name: 3-CHLORO-2,4-DIFLUOROANILINE 99
• Synonyms: 3-CHLORO-2,4-DIFLUOROANILINE 99;3-Chloro-2,4-difluoroaniline 99%;(3-chloro-2,4-difluoro-phenyl)amine;3-Chloro-2,4-diflurozniline;NSC 10276
• CAS NO: 2613-34-5
• Molecular Formula: C₆H₄ClF₂N
• Molecular Weight: 163.5536
• Mol File: 2613-34-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 60-62°C
• Boiling Point: 222.811 °C at 760 mmHg
• Flash Point: 88.553 °C
• Appearance: /
• Density: 1.459 g/cm³
• Vapor Pressure: 0.0996mmHg at 25°C
• Refractive Index: 1.543
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 2.21±0.10(Predicted)
• CAS DataBase Reference: 3-CHLORO-2,4-DIFLUOROANILINE 99(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-2,4-DIFLUOROANILINE 99(2613-34-5)
• EPA Substance Registry System: 3-CHLORO-2,4-DIFLUOROANILINE 99(2613-34-5)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-37/39
• Hazardous Substances Data: 2613-34-5(Hazardous Substances Data)

Usage

Chemical Properties

off-white solid

InChI:InChI=1/C6H4ClF2N/c7-5-3(8)1-2-4(10)6(5)9/h1-2H,10H2

Upstream product

• 3847-58-3 2,4-difluoro-3-chloro-nitrobenzene 

Downstream Products

• 201849-12-9 2-bromo-5-chloro-4,6-difluoroaniline 
• 1075215-57-4 N'-(3-chloro-2,4-difluorophenyl)-N-(4-chloro-6-morpholin-4-yl-pyridin-2-yl)-N'-methyl-pyrimidine-2,4-diamine 
• 1051896-03-7 N'-(3-chloro-2,4-difluoro-phenyl)-N'-methyl-N-(3-morpholin-4-yl-5-thiomorpholin-4-yl-phenyI)pyrimidine-2,4-diamine 
• 1051896-43-5 N'-(3-chloro-2,4-difluoro-phenyl)-N'-methyl-N-[3-(4-methylpiperazin-1-yl)-5-methylsulfonyl-phenyl]pyrimidine-2,4-diamine 
• 1051899-84-3 2-chloro-N-(3-chloro-2,4-difluoro-phenyl)-N-methyl-pyrimidin-4-amine 

Relevant articles and documents

Benzo[f]naphtyridones: A new family of topical antibacterial agents active on multi-resistant Gram-positive pathogens

The synthesis and antibacterial activity of benzo[f][1,7]naphtyridone derivatives are reported. These compounds are potent antibacterial agents with a Gram-positive spectrum of activity. They are active against multi-resistant cocci, especially Staphyloco

Process for the preparation of fluoroanilines from fluorinated nitrated benzene compounds

The instant invention relates to a process for the preparation of fluoroanilines of formula (I) wherein a fluorinated nitrated benzene compound of formula (II) is subjected to a catalytic hydrogenation in a liquid medium containing a catalyst, under hydrogen pressure, carrying out a catalytic reduction reaction and, optionally, a hydrogenolysis reaction, wherein the compound of formula (II) is introduced gradually into the said medium so that the content of compound of formula (II) in the liquid remains less than or equal to 1000 ppm by mass, in order selectively to form the compound of formula (I).