261352-44-7Relevant articles and documents
A new concise synthesis of arcyriacyanin A and its unique inhibitory activity against a panel of human cancer cell line
Murase, Masayuki,Watanabe, Kazuhiro,Yoshida, Takuji,Tobinaga, Seisho
, p. 81 - 84 (2007/10/03)
The nucleophilic addition reaction of N-tosyl-4-oxo-4,5,6,7- tetrahydroindole (12) with the lithium salt of 1-methoxyindole (5), followed by dehydration with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) gave the derivative of 2,4'-bi-1H-indole (9) which provides a new concise synthetic method of an indole pigment of the slime mould, arcyriacyanin A. The compound was first demonstrated here to have unique inhibitory activity to a panel of human cancer cell lines and to inhibit protein kinase C and protein tyrosine kinase.