261512-47-4Relevant articles and documents
NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE
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Page/Page column 148, (2008/12/04)
The present invention provides new compounds of formula I, wherein Q, R1, R2, R4, R5, R6, Xi, R7, R8, M and G1 nare defined as in formula I; invention compounds are modulators of follicle-stimulating hormone - ("FSH") which are useful for male and female contraception as well as other disorders modulated by FSH receptor.
Synthesis and biological evaluation of 1,2,4- triazinylphenylalkylthiazolecarboxylic acid esters as cytokine-inhibiting antedrugs with strong bronchodilating effects in an animal model of asthma
Freyne, Eddy J.,Lacrampe, Jean F.,Deroose, Frederik,Boeckx, Gustaaf M.,Willems, Marc,Embrechts, Werner,Coesemans, Erwin,Willems, Johan J.,Fortin, Jerome M.,Ligney, Yannick,Dillen, Lieve L.,Cools, Willy F.,Goossens, Jan,Corens, David,De Groot, Alex,Van Wauwe, Jean P.
, p. 2167 - 2175 (2007/10/03)
The influx of leukocytes (eosinophils, lymphocytes, and monocytes) into the airways and their production of proinflammatory cytokines contribute to the severity of allergic asthma. We describe here the synthesis and pharmacological evaluation of a series
IL-5 inhibiting 6-azauracil derivatives
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, (2008/06/13)
The present invention is concerned with the compounds of formula the N-oxides, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein p is 0 to 4; X is O, S, NR5 or a direct bond; Y is O, S, NRs