261617-85-0Relevant articles and documents
A facile route to bulladecin-type acetogenins - Total synthesis of asimilobin and correction of the configuration of its tetrahydrofuran segment
Wang, Zhi-Min,Tian, Shi-Kai,Shi, Min
, p. 349 - 356 (2000)
The most efficient method for the synthesis of the trans/threo/trans- bis(tetrahydrofuran) (THF) ring unit was established, and the first total synthesis of (-)-asimilobin and its diastereomer was then accomplished in twelve and fourteen steps, respectively, from trans-1,5,9-decatriene, by a convergent route with a Wittig reaction as the key step. By virtue of these synthetic results, the absolute configuration of the bis(THF) unit in naturally occurring asimilobin should be corrected.