261634-36-0Relevant articles and documents
The sulfamate functional group as a new anchor for solid-phase organic synthesis
Ciobanu, Liviu C.,Maltais, Rene,Poirier, Donald
, p. 445 - 448 (2000)
(Formula presented) Sulfamate derivatives were loaded on trityl chloride resin, and two variants of cleavage were developed for this sulfamate anchor: an acid treatment to easily restore the free sulfamate and a nucleophilic treatment to generate the corresponding phenol. In addition to loading/ cleavage assays and stability experiments, a model sequence of reactions was performed with the new sulfamate anchor to show its applicability in further combinatorial solid-phase synthesis of libraries of biologically relevant sulfamate derivatives.