26171-04-0 Usage
General Description
1-Ethyl-2-(nitromethylene)pyrrolidine, also known as ENP, is a chemical compound that belongs to the class of nitrones. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. The chemical has a nitro group and a pyrrolidine ring structure, making it suitable for various applications in organic synthesis. ENP is known for its ability to act as a chiral building block and is often used in the preparation of chiral ligands and catalysts. Additionally, it has been studied for its potential biological activities, including its role as a potential anti-cancer agent. Overall, 1-Ethyl-2-(nitromethylene)pyrrolidine has a wide range of applications and is an important intermediate in the production of various chemical compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 26171-04-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,1,7 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 26171-04:
(7*2)+(6*6)+(5*1)+(4*7)+(3*1)+(2*0)+(1*4)=90
90 % 10 = 0
So 26171-04-0 is a valid CAS Registry Number.
26171-04-0Relevant articles and documents
A 1 - ethyl - 2 - nitro-methylene pyrrolidine synthetic method (by machine translation)
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Paragraph 0012; 0013; 0014; 0015; 0016; 0017; 0018, (2017/07/20)
The invention relates to a 1 - ethyl - 2 - nitro-methylene pyrrolidine synthetic method, the synthetic method 1 - ethyl pyrrolidone (I) as raw materials, the reaction solvent is added first, then adding phosphorus oxychloride or thionyl chloride, so that the 1 - ethyl pyrrolidone (I) and phosphorus oxychloride or thionyl chloride through Vilsmeier reaction to obtain the Vilsmeier salt intermediate (II); Vilsmeier salt intermediate (II) with nitromethane and sodium methoxide methanol solution obtained by reaction of 1 - ethyl - 2 - nitro-methylene pyrrolidine (III); synthetic route thereof is: . The advantage of this invention lies in: through the synthetic method of this invention, can make the 1 - ethyl - 2 - nitro-methylene pyrrolidine with higher yield, yield can be up to 70% or more, and the synthesizing method, simple and easy to operate, is suitable for the corresponding to the industrial production. (by machine translation)
