261763-02-4

Basic information

• Product Name: 3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)BENZALDEHYDE
• Synonyms: TIMTEC-BB SBB003313;5-CHLORO-6,ALPHA,ALPHA,ALPHA-TETRAFLUORO M-TOLUALDEHYDE;3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)BENZALDEHYDE;3-CHLORO-2-FLUORO-5-(TRIFLUORORMETHYL) B;5-chloro-6,ααα-tetrafluoro m-tolualdehyde;3-Chloro-2-fluoro-5-(triflroromethyl)benzaldehyde, 95%
• CAS NO: 261763-02-4
• Molecular Formula: C₈H₃ClF₄O
• Molecular Weight: 226.56
• EINECS: -0
• Product Categories: Benzaldehyde
• Mol File: 261763-02-4.mol

Chemical Properties

• Boiling Point: 196 °C(lit.)
• Flash Point: 205 °F
• Appearance: /
• Density: 1.54 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.401mmHg at 25°C
• Refractive Index: n20/D 1.476(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• Sensitive: Air Sensitive
• CAS DataBase Reference: 3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)BENZALDEHYDE(261763-02-4)
• EPA Substance Registry System: 3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)BENZALDEHYDE(261763-02-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 261763-02-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Chloro-2-fluoro-5-(trifluoromethyl)benzaldehyde is used as an intermediate in the production of various pharmaceuticals. Its unique structure and reactivity allow for the synthesis of a wide range of drug molecules, contributing to the development of new therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical industry, 3-chloro-2-fluoro-5-(trifluoromethyl)benzaldehyde serves as a key intermediate for the synthesis of various agrochemicals. Its incorporation into these compounds can enhance their effectiveness in pest control and crop protection.
Used in Specialty Polymers and Materials:
3-Chloro-2-fluoro-5-(trifluoromethyl)benzaldehyde is utilized in the synthesis of specialty polymers and materials due to its distinct chemical properties. Its incorporation can impart specific characteristics to these materials, broadening their applications in various industries.
Used in Medicinal Chemistry and Drug Discovery:
3-Chloro-2-fluoro-5-(trifluoromethyl)benzaldehyde may have potential applications in the field of medicinal chemistry and drug discovery. Its unique structure and reactivity can be leveraged to design and develop novel drug candidates with improved pharmacological properties and therapeutic potential.

InChI:InChI=1/C8H3ClF4O/c9-6-2-5(8(11,12)13)1-4(3-14)7(6)10/h1-3H

Upstream product

• 78068-85-6 3-chloro-4-fluoro benzotrifluoride 
• 68-12-2 N,N-dimethyl-formamide 
• 1198578-80-1 sodium (3-chloro-2-fluoro-5-trifluoromethyl-phenyl)-hydroxy-methanesulfonate 

Downstream Products

• 1154416-07-5 tert-butyl 2,6,6-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1154416-14-4 tert-butyl 2,7,7-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1154416-04-2 allyl 2,6,6-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1154416-11-1 allyl 2,7,7-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1154416-06-4 isobutyl 2,6,6-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1154416-13-3 isobutyl 2,7,7-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1154416-08-6 benzyl 2,6,6-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1154416-05-3 2-methoxyethyl 2,6,6-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1154416-03-1 ethyl 2,6,6-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1154416-02-0 methyl 2,6,6-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1154416-15-5 benzyl 2,7,7-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1154416-12-2 2-methoxyethyl 2,7,7-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1154416-10-0 ethyl 2,7,7-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1154416-09-7 methyl 2,7,7-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES

The present invention comprises a process for the preparation of 3-chloro-2-fluoro-5-trifluoromethyl benzoic acid of the formula or of a salt thereof. 3-Chloro-2-fluoro-5-trifluoromethyl benzoic acid or salts thereof are versatile intermediates for the preparation of active pharmaceutical or agrochemical agents.