261786-56-5Relevant articles and documents
Synthesis and anti-HIV activity of cosalane analogues incorporating nitrogen in the linker chain
Casimiro-Garcia, Agustin,De Clercq, Erik,Pannecouque, Christophe,Witvrouw, Myriam,Stup, Tracy L.,Turpin, Jim A.,Buckheit Jr., Robert W.,Cushman, Mark
, p. 191 - 200 (2000)
Introduction of an amido group or an amino moiety into the alkenyl linker chain of cosalane (1) provided a new series of analogues 3-8. The new compounds were evaluated as inhibitors of the cytopathic effect of HIV-1 and HIV-2 in cell culture. The replace