2619-00-3

Basic information

• Product Name: 1-Naphthyl N,N-dimethylcarbamate
• Synonyms: 1-Naphthyl N,N-dimethylcarbamate;Dimethylcarbamic acid 1-naphtyl ester;N,N-Dimethylcarbamic acid 1-naphtyl ester
• CAS NO: 2619-00-3
• Molecular Formula: C₁₃H₁₃NO₂
• Molecular Weight: 215.25
• Mol File: 2619-00-3.mol
• Article Data: 6

Chemical Properties

• Melting Point: 51-52 °C
• Boiling Point: 342.8°Cat760mmHg
• Flash Point: 161.1°C
• Appearance: /
• Density: 1.163g/cm³
• Vapor Pressure: 7.33E-05mmHg at 25°C
• Refractive Index: 1.606
• PKA: -1.52±0.70(Predicted)
• CAS DataBase Reference: 1-Naphthyl N,N-dimethylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Naphthyl N,N-dimethylcarbamate(2619-00-3)
• EPA Substance Registry System: 1-Naphthyl N,N-dimethylcarbamate(2619-00-3)

Safety Data

• Hazardous Substances Data: 2619-00-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H13NO2/c1-14(2)13(15)16-12-9-5-7-10-6-3-4-8-11(10)12/h3-9H,1-2H3

Upstream product

• 90-15-3 α-naphthol 
• 79-44-7 N,N-Dimethylcarbamoyl chloride 
• 3759-61-3 1-naphthyl chloroformate 
• 124-40-3 dimethyl amine 

Downstream Products

• 134-32-7 1-amino-naphthalene 
• 4044-57-9 1-phenylethynyl-naphthalene 
• 22871-77-8 5,5-dimethyl-2-(naphthalen-1-yl)-1,3,2-dioxaborinane 
• 14476-01-8 1-o-tolylnaphthalene 
• 86-53-3 1-Cyanonaphthalene 
• 93321-11-0 1-(2-methoxyphenyl)naphthalene 

Relevant articles and documents

Room-temperature Pd-catalyzed C-H chlorination by weak coordination: One-pot synthesis of 2-chlorophenols with excellent regioselectivity

A room-temperature Pd(ii)-catalyzed regioselective chlorination reaction has been developed for a facile one-pot synthesis of a broad range of 2-chlorophenols. The reaction demonstrates an excellent regioselectivity and reactivity for C-H chlorination. This reaction represents one of the rare examples of mild C-H functionalization at ambient temperature.

Microwave-promoted copper-free Sonogashira-Hagihara couplings of aryl imidazolylsulfonates in water

Aryl imidazol-1-ylsulfonates have been efficiently cross-coupled with aryl-, alkyl-, and silylacetylenes in neat water under copper-free conditions at 110 °C assisted by microwave irradiation. Using 0.5mol% of an oxime palladacycle as precatalyst, 2-dicyclohexylphosphino-2′,6′- dimethoxybiphenyl (SPhos, 2mol%) as ligand, hexadecyltrimethylammonium bromide (CTAB) as additive, and triethylamine (TEA) as base, a wide array of disubstituted alkynes has been prepared in good to high yields in only 30min. Copyright

Phosphane-free suzukimiyaura coupling of aryl imidazolesulfonates with arylboronic acids and potassium aryltrifluoroborates under aqueous conditions#

Aryl imidazole-1-sulfonates are efficiently cross-coupled with arylboronic acids and potassium aryltrifluoroborates using only 0.5 mol% of oxime palladacycles 1 under aqueous conditions at 110 °C. Under these simple phosphane-free reaction conditions a wide array of biaryl derivatives has been prepared in high yields. This methodology allows in situ phenol sulfonation and one-pot Suzuki arylation as well as the employment of microwave irradiation conditions.