261920-70-1Relevant academic research and scientific papers
Regioselective synthesis of 1-allyl- and 1-arylmethyl uracil and thymine derivatives
Malik, Vaishali,Singh, Palwinder,Kumar, Subodh
, p. 4009 - 4014 (2007/10/03)
2,4-Bis(trimethylsiloxy) pyrimidines 1 with allyl halides and arylmethyl halides in 1,2-dichloroethane in the presence of I2 regioselectively provide 1-allyl-/1-arylmethyl-uracil and thymine derivatives. The secondary aryl alkyl and diaryl meth
An efficient synthesis of pyrimidines from beta-amino alcohols.
Agami,Dechoux,Melaimi
, p. 633 - 634 (2007/10/03)
[reaction: see text] Pyrimidinones 3 were chemoselectively reduced by using metal-catalyzed hydrogenation and stereoselectively substituted by various nucleophiles. Starting from beta-amino alcohols 1, the overall process allows efficient access to substi
