26195-77-7Relevant academic research and scientific papers
2-(4-R-Phenoxy/phenylthio)alkanoic esters of l-lupinine
Sparatore, Anna,Sparatore, Fabio
, p. 169 - 174 (2001)
Considering the great pharmacological interest in phenoxy/phenylthioalkanoic esters of open-chain or cyclic aminoalcohols, a set of ten such esters of lupinine was prepared. Initially, their ability to displace [3H]QNB from rat brain preparation was investigated. With the exception of two, all the prepared esters exhibited good affinity to muscarinic receptors (on a non-selective basis), with pKi in the range 6.67-7.68.
