261967-40-2Relevant academic research and scientific papers
A silicon-mediated domino approach to pyrrolidine- and piperidine-2,3-diones
Jungf, Alexander,Koch, Oliver,Ries, Monika,Schaumann, Ernst
, p. 92 - 94 (2007/10/03)
Lithiated silylthioacetals 1 react with co-bromoalkyl isocyanates 2 via addition to the isocyanate, a 1,3-silyl shift and ringclosure by bromide displacement to give lactams 6. The latent α-oxo group can be liberated by thioacetal cleavage with hypervalen
