26198-65-2Relevant academic research and scientific papers
Utilizing an iron(III)-chelation masking strategy to prepare mono- and bis-functionalized aerobactin analogues for targeting pathogenic bacteria
Ho, Yu-Hin,Ho, Sheng-Yang,Hsu, Cheng-Chih,Shie, Jiun-Jie,Wang, Tsung-Shing Andrew
, p. 9265 - 9268 (2017)
A direct and selective method for the functionalization of aerobactin has been described. Selectivity was achieved by masking the functioning carboxylate via iron-chelation, leaving the two remaining carboxylates for direct modification. Both mono- and bis-functionalized aerobactin effectively targeted pathogenic bacteria, showing a facile method with prospective applications.
