26207-69-2Relevant academic research and scientific papers
The Reversible Cyclization of a Chalcone, 1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-ethoxyphenyl)prop-2-en-1-one: a Kinetic and Mechanistic Study
Button, Richard G.,Taylor, Peter J.
, p. 1571 - 1580 (2007/10/02)
Cyclization of the title 2'-hydroxychalcone 1 to the flavanone 2 in 30percent v/v isopropyl alcohol is a reversible process with a complex rate-pH profile.In alkali, while the forward reaction goes through the anion of 1, its reverse goes via a hydroxide
