76554-22-8Relevant academic research and scientific papers
Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux
Lorendeau, Doriane,Dury, Lauriane,Genoux-Bastide, Estelle,Lecerf-Schmidt, Florine,Sim?es-Pires, Claudia,Carrupt, Pierre-Alain,Terreux, Rapha?l,Magnard, Sandrine,Di Pietro, Attilio,Boumendjel, Ahcène,Baubichon-Cortay, Hélène
, p. 235 - 245 (2014/07/21)
The multidrug resistance protein 1 (MRP1) is involved in multidrug resistance of cancer cells by mediating drug efflux out of cells, often in co-transport with glutathione (GSH). GSH efflux mediated by MRP1 can be stimulated by verapamil. In cells overexp
The Reversible Cyclization of a Chalcone, 1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-ethoxyphenyl)prop-2-en-1-one: a Kinetic and Mechanistic Study
Button, Richard G.,Taylor, Peter J.
, p. 1571 - 1580 (2007/10/02)
Cyclization of the title 2'-hydroxychalcone 1 to the flavanone 2 in 30percent v/v isopropyl alcohol is a reversible process with a complex rate-pH profile.In alkali, while the forward reaction goes through the anion of 1, its reverse goes via a hydroxide
