26209-66-5

Basic information

• Product Name: 2-Piperidinone, 1-(2-phenylethyl)-
• CAS NO: 26209-66-5
• Molecular Formula: C13H17NO
• Molecular Weight: 203.284
• Mol File: 26209-66-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Piperidinone, 1-(2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Piperidinone, 1-(2-phenylethyl)-(26209-66-5)
• EPA Substance Registry System: 2-Piperidinone, 1-(2-phenylethyl)-(26209-66-5)

Safety Data

• Hazardous Substances Data: 26209-66-5(Hazardous Substances Data)

Upstream product

• 779-52-2 1-phenyl-2-piperidin-1-yl-ethanone 
• 3553-93-3 1-(trimethylsilyl)piperidin-2-one 
• 103-63-9 1-phenyl-2-bromoethane 
• 1441640-24-9 7-azido-1-phenylheptan-3-one 
• 104-53-0 3-phenyl-propionaldehyde 
• 918648-48-3 7-chloro-1-phenyl-3-heptanone 
• 70-11-1 α-bromoacetophenone 
• 110-89-4 piperidine 
• 89241-15-6 2-Phenethyl-1-oxa-2-aza-spiro[2.4]heptane 

Relevant articles and documents

Overcoming product inhibition in catalysis of the intramolecular Schmidt reaction

A method for carrying out the intramolecular Schmidt reaction of alkyl azides and ketones using a substoichiometric amount of catalyst is reported. Following extensive screening, the use of the strong hydrogen-bond-donating solvent hexafluoro-2-propanol was found to be consistent with low catalyst loadings, which ranged from 2.5 mol % for favorable substrates to 25 mol % for more difficult cases. Reaction optimization, broad substrate scope, and preliminary mechanistic studies of this improved version of the reaction are described.

Cyclic Allylamine-Enamine Systems. Part 8. Isomerisation Using Rhodium Complexes. 3-Aminoalkylidene-3H-indoles. Part 5. 6,7-Dihydroindoloquinolizine and 1,2,3,4,6,7-Hexahydroindoloquinolizine

The use of rhodium-complex catalysis for cyclic allylamine --> cyclic enamine isomerisation is described.Indoloquinolizines are produced using this methodology and also via 3-amino-3H-indole intermediates.N-alkylation of N-silylated amides is described.