26228-68-2

Usage

Uses

Used in Chemical Synthesis:
4-(Aminomethyl)-1-methyl-piperidin-4-ol is used as a building block in chemical synthesis for its versatile functional groups, which allow for the creation of various chemical compounds and intermediates.
Used in Pharmaceutical Applications:
In the pharmaceutical industry, 4-(Aminomethyl)-1-methyl-piperidin-4-ol is utilized as a key component in the development of new drugs. Its unique structure and functional groups enable it to be incorporated into medicinal compounds, potentially leading to the discovery of novel therapeutic agents.
Used in Research and Development:
4-(Aminomethyl)-1-methyl-piperidin-4-ol is employed as a research tool in the field of organic chemistry and medicinal chemistry. Its properties and reactivity are studied to gain insights into the synthesis of new compounds and to understand the underlying chemical reactions.
Used in Material Science:
Although not explicitly mentioned in the provided materials, the compound's structural features may also find applications in material science, where its amine and alcohol groups could be utilized in the development of new materials with specific properties, such as polymers or coatings.

InChI:InChI=1/C7H16N2O/c1-9-4-2-7(10,6-8)3-5-9/h10H,2-6,8H2,1H3

Upstream product

• 392331-66-7 4-aminomethyl-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester 
• 1445-73-4 1-Methyl-4-piperidone 
• 150358-78-4 4-Cyano-4-trimethylsilyloxy-1-methyl-piperidine 
• 116250-49-8 1-methyl-4-(nitromethyl)piperidin-4-ol 

Downstream Products

• 5053-07-6 8-methyl-1-oxa-3,8-diaza-spiro[4.5]decan-2-one 
• 1225379-48-5 1-methyl-4-[({5-[(5-methyl-3-{3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl}-1H-pyrazol-1-yl)methyl]pyridin-2-yl}amino)methyl]piperidin-4-ol 
• 1361951-07-6 1-methyl-4-(((3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-yl)amino)methyl)piperidin-4-ol 
• 138300-83-1 4-acetamidomethyl-4-hydroxy-1-methylpiperidine 

Relevant academic research and scientific papers

Histone Deacetylase Inhibitors and Methods of Use Thereof

The present invention relates to methods of modulating activity of histone deacetylases (HDACs). The present invention also relates to methods of treating HDAC-associated diseases including, but not limited to, cancers, inflammatory disorders, and neurodegenerative disorders. The present invention also provides novel compounds and compositions thereof and methods of preparation of the same. The present invention also includes methods of inhibiting HDACs, and methods of treating HDAC-associated diseases using the compounds of the invention.

Substituted imidazo[1,2-b]pyridazines as protein kinase inhibitors

The present invention provides protein kinase having one of the following structures (I), (II) or (III): or a stereoisomer, prodrug, tautomer or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer, autoimmune, inflammatory and other Pim kinase-associated conditions are also disclosed.

QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR INHIBITORS

Compounds of formula (Ι') that are Fibroblast Growth Factor Inhibitors (FGFR) and are therefore useful for the treatment of diseases treatable by inhibition of FGFR are disclosed. Also disclosed are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

HETEROCYCLIC PROTEIN KINASE INHIBITORS

The present invention provides protein kinase having one of the following structures (I), (II) or (III): or a stereoisomer, prodrug, tautomer or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer, autoimmune, inflammatory and other Pim kinase-associated conditions are also disclosed.

Pyrrolo [3,2-C] Pyridine-4-One 2-Indolinone Protein Kinase Inhibitors

The present invention relates to pyrrolo[3,2-c]pyridine-4-one 2-indolinone compounds of Formula (I) and their pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8X, Y and have the meaning cited in the specification.

PYRROLO [3,2-C] PYRIDINE-4-ONE 2-INDOLINONE PROTEIN KINASE INHIBITORS

The present invention relates to pyrrolo[3,2-c]pyridine-4-one 2-indolinone compounds of Formula (I) and their pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8 X , Y and …. have the meaning cited in the specifica

SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES

Imidazo-quinoline, -pyridine, and -naphthyridine ring systems (particularly quinolines, tetrahydroquinolines, pyridines, [1,5]naphthyridines, [1,5]tetrahydronaphthyridines) substituted at the 1-position with a cyclic substituent, pharmaceutical compositions containing the compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.