2627-62-5

Basic information

• Product Name: 2'-chloro-2'-deoxyadenosine
• Synonyms: 2'-Chloro-2'-deoxyadenosine;2'-Deoxy-2'-chloroadenosine; NSC 289354
• CAS NO: 2627-62-5
• Molecular Formula: C10H12 Cl N5 O3
• Molecular Weight: 285.69
• Mol File: 2627-62-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 678.2°Cat760mmHg
• Flash Point: 364°C
• Appearance: /
• Density: 2.03g/cm³
• CAS DataBase Reference: 2'-chloro-2'-deoxyadenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-chloro-2'-deoxyadenosine(2627-62-5)
• EPA Substance Registry System: 2'-chloro-2'-deoxyadenosine(2627-62-5)

Safety Data

• Hazardous Substances Data: 2627-62-5(Hazardous Substances Data)

Upstream product

• 88121-20-4 3′,5′-O-(1,1,3,3-tetraisopropyldisiloxyl)-2′-O-(trifluormethylsulfonyl)adenosine 
• 69304-45-6 3',5'-O-(1,1,3,3-tetra-isopropyldisiloxane-1,3-diyl)adenosine 
• 85335-82-6 3',5'-O-(1,1,3,3-tetraisopropyldisilox-1,3-diyl)-9-(2-chloro-2-deoxy-β-D-arabinofuranosyl)adenine 

Downstream Products

• 13276-53-4 9-(2'-deoxy-β-D-threo-ribofuranosyl)-adenine 
• 184297-08-3 Thiocarbonic acid O-[(2R,3R,4S,5R)-5-(6-amino-purin-9-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-4-chloro-tetrahydro-furan-3-yl] ester O-phenyl ester 
• 184297-04-9 Thiocarbonic acid O-[(2R,3R,4R,5R)-5-(6-amino-purin-9-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-4-chloro-tetrahydro-furan-3-yl] ester O-phenyl ester 

Relevant articles and documents

Deoxygenative [1,2]-hydride shift rearrangements in nucleoside and sugar chemistry: Analogy with the [1,2]-electron shift in the deoxygenation of ribonucleotides by ribonucleotide reductases

(Chemical Equation Presented) A variant of the semipinacol rearrangement that was observed in our laboratory has been applied to the synthesis of several furanose and pyranose derivatives. The process consists of an "orchestrated" [1,2]-hydride shift with

Synthesis of 2'-substituted derivatives of neplanocin A (nucleosides and nucleotides. XLIV)

-

Nucleic acid related compounds.22. Transformation of ribonucleoside 2,3'-O-ortho esters into halo, deoxy, and epoxy sugar nucleosides using acyl halides. Mechanism and structure of products.

-