26295-46-5Relevant academic research and scientific papers
Oxaliplatin derived monofunctional triazole-containing platinum(II) complex counteracts oxaliplatin-induced drug resistance in colorectal cancer
Li, Yaru,Sun, Ziru,Cui, Yujun,Zhang, Heming,Zhang, Shunjie,Wang, Xinyu,Liu, Shengnan,Gao, Qingzhi
, (2021)
Oxaliplatin-based chemotherapy is the current standard of care in adjuvant therapy for advanced colorectal cancer (CRC). But acquired resistance to oxaliplatin eventually occurs and becoming a major cause of treatment failure. Thus, there is an unmet need
Synthesis of a Series of a Few Hydrosulfide Complexes of Cu(I). A μ3-SH-Bridged Rare Cubane-like Tetramer Showing Efficient Catalytic Activity toward Azide-Alkyne Cycloaddition
Nayak, Mousumi,Joshi, Deepak K.,Kumar, Krishna,Singh, Anoop S.,Tiwari, Vinod K.,Bhattacharya, Subrato
supporting information, p. 8075 - 8084 (2021/06/27)
A cubane-like tetranuclear hydrosulfido complex of Cu(I), [Cu4(SH)4(PPh3)4] (1), has been synthesized by the reaction of Cu(NO3)2·3H2O, NaSCOPh, and Cu(PPh3)2NO3 and characterized structurally. Complex 1 represents the first example of crystallographically characterized μ3-SH-bridged cubanoid hydrosulfide. By direct reactions of [(PPh3)2Cu(NO3)] and NaSH, neutral hydrosulfide complexes [Cu(SH)(PPh3)2]·C6H6 (2), [Cu2(SH)2(PPh3)3] (3), and [Cu2(SH)2(PPh3)4] (4) have also been synthesized and structurally characterized. Complex 2 is monomeric with a terminal hydrosulfide ligand. The other two, 3 and 4, are μ2-SH-bridged unsymmetrical and symmetrical dinuclear complexes, respectively. In the symmetric one (4), both Cu(I) ions are tetrahedrally coordinated while in the unsymmetric one (3), one Cu(I) ion is tetrahedral and the other one has a trigonal-planar coordination geometry. The catalytic activity of a hydrosulfido complex in a "click"azide-alkyne cycloaddition reaction has been explored for the first time, and complex 1 is found to be an efficient catalyst for the regioselective synthesis of glycoconjugate triazoles.
Sonochemical Decoration of Graphene Oxide with Magnetic Fe3O4@CuO Nanocomposite for Efficient Click Synthesis of Coumarin-Sugar Based Bioconjugates and Their Cytotoxic Activity
Jain, Yachana,Kumari, Mitlesh,Singh, Raman Preet,Kumar, Deepak,Gupta, Ragini
, p. 1142 - 1154 (2019/11/03)
Abstract: A magnetic nanocomposite of GO-Fe3O4@CuO was fabricated via a simple sonochemical technique and successfully utilized for the ultrasound promoted synthesis of regioselective 1,4-disubstituted mono/bis/tris-1,2,3-triazoles (
N-glycosylation reaction of thio-glycoside using hypervalent iodine(III) reagent
Ikeda, Takumi,Kajimoto, Tetsuya,Kita, Yasuyuki,Morimoto, Koji,Uchikawa, Chihiro,Yanase, Kana
, p. 621 - 630 (2020/01/31)
We discovered that the hypervalent iodine(III) reagent could mediate the N-glycosylation reaction using the thio-glycoside donors with triazoles. By using this method, glycosyl triazole could be easily synthesized under mild reaction conditions.
Catalytic activity of new heteroleptic [Cu(PPh3)2(β-oxodithioester)] complexes: Click derived triazolyl glycoconjugates
Kumari, Kavita,Singh, Anoop S.,Manar, Krishna K.,Yadav, Chote Lal,Tiwari, Vinod K.,Drew, Michael G.B.,Singh, Nanhai
supporting information, p. 1166 - 1176 (2019/01/21)
A series of four new and two known luminescent heteroleptic Cu(i) complexes of the form [Cu(PPh3)2(β-oxodithioester)] (β-oxodithioester = methyl-3-hydroxy-3-(2-furyl)-2-propenedithioate L1 1, methyl-3-hydroxy-3-(2-thienyl)-2-propened
Highly efficient structurally characterised novel precatalysts: Di- and mononuclear heteroleptic Cu(i) dixanthate/xanthate-phosphine complexes for azide-alkyne cycloadditions
Anamika,Agrahari, Anand K.,Manar, Krishna K.,Yadav, Chote Lal,Tiwari, Vinod K.,Drew, Michael G. B.,Singh, Nanhai
supporting information, p. 8939 - 8949 (2019/06/17)
Novel heteroleptic dinuclear [Cu2(L)(PPh3)4] (L = 2,6-pyridinedimethyldixanthate L1 1, 1,4-benznedimethyldixanthate L2 2, 1,4-cyclohexanedixanthate L3 3) and mononuclear [Cu(L4)(PPh3)2] 4 (L4 = pipero
Highly efficient and recyclable pre-catalysts based on mono- and dinuclear heteroleptic Cu(I) dithio- PPh3 complexes to produce variety of glycoconjugate triazoles
Singh, Avadhesh K.,Yadav, Chote Lal,Mishra, Kunj Bihari,Singh, Santosh K.,Gupta, Ajit N.,Tiwari, Vinod Kumar,Drew, Michael G.B.,Singh, Nanhai
, p. 152 - 163 (2019/04/25)
Highly efficient and reusable pre-formed mono- and dinuclear heteroleptic copper(I) dithiocarbamate and dithiocarbimate complex based catalysts, [Cu(PPh3)2(L)] and [Cu2(PPh3)4(L)] (L = N-(4-methylpyri
Preparation method for synthesizing 1,4-substituted 1,2,3-triazole from organic azide and terminal alkynes
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Paragraph 0078; 0079, (2019/12/25)
The invention belongs to the technical field of nitrogen-containing compound preparation, discloses a preparation method for synthesizing 1,4-substituted 1,2,3-triazole from organic azide and terminalalkynes, provides a method which is used for preparing
Method for synthesizing P-1,4- substituted triazole 1, 2, 3- in alkynylic acid (by machine translation)
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Paragraph 0099-0100, (2019/12/09)
The method comprises the following steps: adding water to a reaction bottle; adding water to 1,4 - the 1, 2, 3 - reaction flask; adding water; extracting with ethyl acetate; extracting with 1.2 ethyl acetate; 1.0 adding ethyl acetate; 0.05 drying the ethy
A dinuclear copper(i) thiodiacetate complex as an efficient and reusable 'click' catalyst for the synthesis of glycoconjugates
Sareen, Neha,Singh, Anoop S.,Tiwari, Vinod K.,Kant, Rajni,Bhattacharya, Subrato
supporting information, p. 12705 - 12710 (2017/10/06)
We report herein the facile synthesis and structural characterization of a highly stable dinuclear Cu(i) complex, [(PPh3)2Cu(μ-tda)Cu(PPh3)2]·6H2O 1 (tda = thiodiacetate anion), in which the Cu-Cu dis
