263016-97-3Relevant academic research and scientific papers
Amino alcohol derivatives
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Page 111, (2010/11/30)
Compounds of formula (I) which exhibit excellent immune suppression activity, pharmacologically acceptable salts thereof, esters thereof or other derivatives: wherein R1 and R2 are a hydrogen atom, an amino protecting group; R3 is a hydrogen atom, a hydroxy protecting group; R4 is a lower alkyl group; n is an integer from 1 to 6; X is an ethylene group; Y is a C1-C10 alkylene group, a C1-C10 alkylene group substituted with 1 to 3 substituents selected from substituent group a and b; R5 is an aryl group; R6 and R7 are a hydrogen atom, a group selected from substituent group a; with the proviso when R5 is a hydrogen atom, Y is not a single bond or a straight chain C1-C10 alkylene group.
A straightforward synthesis of both enantiomers of α-vinylalanine and α-ethynylalanine
Avenoza, Alberto,Cativiela, Carlos,Peregrina, Jesus M.,Sucunza, David,Zurbano, Maria M.
, p. 4653 - 4661 (2007/10/03)
This report describes the synthesis of enantiomerically pure (S)- and (R)-α-vinylalanines and (S)- and (R)-α-ethynylalanines, four quaternary α- amino acids, using a straightforward synthetic route and starting from (S)- and (R)-N-Boc-N,O-isopropylidene-α-methylserinals. (C) 1999 Elsevier Science Ltd.
