26326-86-3

Basic information

• Product Name: INS(1,2,4,5,6)P5
• Synonyms: D-MYO-INOSITOL-1,2,4,5,6-PENTAKISPHOSPHATE;INS(1,2,4,5,6)P5;L-myo-Inositol 2,3,4,5,6-pentakis-phosphate
• CAS NO: 26326-86-3
• Molecular Formula: C₆H₁₇O₂₁P₅
• Molecular Weight: 580.06
• Mol File: 26326-86-3.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: ?20°C
• CAS DataBase Reference: INS(1,2,4,5,6)P5(CAS DataBase Reference)
• NIST Chemistry Reference: INS(1,2,4,5,6)P5(26326-86-3)
• EPA Substance Registry System: INS(1,2,4,5,6)P5(26326-86-3)

Safety Data

• Hazardous Substances Data: 26326-86-3(Hazardous Substances Data)

Upstream product

• 17211-15-3 sodium inositol hexaphosphate 
• 28841-60-3 D-myo-inositol 1,4,5,6-tetrakisphosphate 
• 211294-79-0 (3aS,4R,5R,5aR,8aR,8bR)-2,2,7,7-Tetramethyl-hexahydro-benzo[1,2-d;3,4-d']bis[1,3]dioxole-4,5-diol 
• 211294-76-7 Acetic acid (3aR,4R,5S,5aR,8aR,8bS)-5-hydroxy-2,2,7,7-tetramethyl-hexahydro-benzo[1,2-d;3,4-d']bis[1,3]dioxol-4-yl ester 
• 165883-86-3 D-3-O-benzoyl-myo-inositol 
• 38643-30-0 (±)-1,2:5,6-di-O-isopropylidene-myo-inositol 

Downstream Products

• 573-35-3 myo-Inositol 2-phosphate 
• 28841-62-5 D-myo-inositol 1,2,6-trisphosphate 

Relevant articles and documents

Roles of phosphate recognition in inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IPK1) substrate binding and activation

Background: The mechanism of substrate recognition for IPK1 (inositol 1,3,4,5,6-pentakisphosphate 2-kinase) is unresolved. Results: Binding and activity data reveal specific roles for each phosphate of IP5. Conclusion: The phosphate profile of IP5 is mech

Flexible stereo- and regioselective synthesis of myo-inositol phosphates (Part 2): Via nonsymmetrical conduritol B derivatives

A practical route is described for the preparation of myo-inositol phosphates. Optically pure compounds can be prepared, in both forms, from p-benzoquinone by enzymatic resolution of a diacetoxyconduritol key intermediate. Monosubstituted inositol derivat

The pathway of dephosphorylation of myo-inositol hexakisphosphate by phytases from wheat bran of Triticum aestivum L. cv. Nourin #61

Phytases are the primary enzymes responsible for the hydrolysis of phytic acid, myo-inositol-1, 2, 3, 4, 5, 6-hexakisphosphate (InsP6). The pathway of hydrolysis of InsP6 by phytase from wheat bran of Triticum aestivum L. cv. Nourin #61 is proved in this study. Structures of the intermediates were established by a variety of nuclear magnetic resonance techniques (1H-, two-dimensional 1H-1H coupling-correlation spectra and two-dimensional 31P-1H correlation spectra), gas chromatography, and bioassay. On the basis of the structures identified, initial hydrolysis of the phosphate ester occurs at the D/L-4 position of InsP6 to yield D/L-Ins (1, 2, 3, 5, 6) P5. After the dephosphorylation, the pathway of dephosphorylation is divided into two routes. The main route proceeds via D/L-Ins (1, 2, 5, 6) P4, D/L-Ins (1, 2, 6) P3 and D/L-Ins (1, 2) P2, while the minor route proceeds via D/L-Ins (1, 2, 3, 6) P4, Ins (1, 2, 3) P3 and D/L-Ins (1, 2) P2. D/L-Ins (1, 2) P2 is hydrolyzed at the D/L-1 or 2-position, and finally myo-inositol is produced.