263351-43-5

Basic information

• Product Name: (3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: tert-Butyl 3-iodobenzylcarbamate;(3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER
• CAS NO: 263351-43-5
• Molecular Formula: C₁₂H₁₆INO₂
• Molecular Weight: 333.16541
• Mol File: 263351-43-5.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER(263351-43-5)
• EPA Substance Registry System: (3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER(263351-43-5)

Safety Data

• Hazardous Substances Data: 263351-43-5(Hazardous Substances Data)

Usage

Description

(3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER, with the chemical formula C11H14INO2, is a white to off-white solid chemical compound. Derived from carbamic acid, it features a tert-butyl ester group that provides stability and ease of handling in laboratory environments. The iodo-benzyl group in its structure renders it valuable for specific organic synthesis applications. Due to its potentially harmful properties, it is crucial to handle this compound with care and appropriate safety measures.

Uses

Used in Organic Synthesis:
(3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER is used as a reagent in organic synthesis for its ability to participate in various chemical reactions, particularly those involving the iodo-benzyl group, which can be a key component in the formation of new compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER is used as an intermediate in the synthesis of pharmaceutical compounds. Its unique structure allows it to be a building block for the development of new drugs, potentially contributing to the creation of medications with novel therapeutic properties.
Used in Chemical Research:
(3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER is utilized as a research tool in chemical laboratories for studying reaction mechanisms and exploring new pathways in chemical synthesis. Its properties make it a valuable asset for scientists looking to understand and innovate within the field of organic chemistry.
Used in Material Science:
In material science, (3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER may be employed in the development of new materials with specific properties. Its chemical structure could contribute to the creation of materials with unique characteristics, such as improved stability or reactivity, depending on the application.

Upstream product

• 1228693-09-1 C₂₃H₂₁F₁₇INO₃ 
• 24424-99-5 di-tert-butyl dicarbonate 
• 696-40-2 3-iodobenzylamine 
• 3718-88-5 3-iodobenzylamine hydrochloride 

Downstream Products

• 1028338-68-2 [3-(3-dimethylamino-propylamino)-benzyl]-carbamic acid tert-butyl ester 
• 1028338-70-6 [3-(2-morpholin-4-yl-ethylamino)-benzyl]-carbamic acid tert-butyl ester 
• 1222138-87-5 tert-butyl [3-[5-[(2(S)-azetidinyl)methoxy]-3-pyridyl]benzyl]carbamate 
• 828242-06-4 tert-butyl N-[(3-pyrrolidin-1-ylphenyl)methyl]carbamate 
• 175696-70-5 (3-(pyrrolidin-1-yl)phenyl)methanamine 
• 913073-73-1 tert-butyl 3-((trimethylsilyl)ethynyl)benzylcarbamate 
• 1309877-90-4 C₂₆H₂₄ClIN₂O 
• 1283596-51-9 C₁₅H₁₂ClN*ClH 

Relevant articles and documents

ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS

The present invention relates to a compound suitable for use as a kinase inhibitor according to general formula (I) [compound (C), herein after], or the N- oxide, pharmaceutically acceptable salt, pharmaceutically acceptable solvate, or stereoisomer thereof, formula (I) wherein A, R1, R2, R3, R3', R4, R4', X, Y, Z, T are as defined in the claims. The invention further relates to an in vitro method of inhibiting protein kinase activity which comprises contacting a protein kinase with a compound of formula (I), or the N-oxide, pharmaceutically acceptable salt, pharmaceutically acceptable solvate, or stereoisomer thereof. The invention further relates to the compounds of formula (I) per se, as well as to their use as a medicament, and for use or in a method of treatment of a disease mediated by a protein kinase selected from cancer, inflammatory disorders, cardiovascular diseases, viral induced diseases, circulatory diseases, fibro-proliferative diseases and pain sensitization disorders.

NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF

The invention relates to pyridinyl nicotinic acetylcholine receptor ligands, compositions comprising an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand and methods to treat or prevent a condition, such as depression and nicotine dependence, comprising administering to an animal in need thereof an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand.

Synthesis and application of a new fluorous-tagged ammonia equivalent

A novel fluorous-tagged ammonia equivalent has been developed. It is based on a nitrogen-oxygen bond, which can be cleaved in a traceless manner by a molybdenum complex or samarium diiodide. The application in the synthesis of ureas, amides, sulfonamides, and carbamates is described. The scope of the fluo-rous N-O linker is exemplified by the synthesis of itopride, a drug used for the treatment of functional dyspepsia. Itopride was synthesized with the aid of fluorous purification methods and the product was isolated in good overall yield, with high purity.