263384-66-3

Upstream product

• 98-09-9 benzenesulfonyl chloride 
• 1019-45-0 N,N-dimethyl-5-methoxytryptamine 
• 107-08-4 1-iodo-propane 
• 263384-65-2 N,N-dimethyl-2-[1-(benzenesulphonyl)-5-methoxy-1H-indol-3-yl]ethylamine 

Relevant academic research and scientific papers

Selective 5-HT6 receptor ligands

Compounds which have enhanced affinity and selectivity for 5-HT6receptors have been identified. These compounds can be used therapeutically in the treatment of mental disorders via administration in a pharmacologically acceptable delivery route to a patient in need thereof, or can be used to identify antagonists of 5-HT6receptors by well known screening methodologies which could themselves be used in the treatment of mental disorders.

2-Substituted tryptamines: Agents with selectivity for 5-HT6 serotonin receptors

Several 2-alkyl-5-methoxytryptamine analogues were designed and prepared as potential 5-HT6 serotonin agonists. It was found that 5-HT6 receptors accommodate small alkyl substituents at the indole 2-position and that the resulting co