263400-88-0 Usage
Description
Toluene-4-sulfonic acid 3-Methanesulfonyl-propyl ester is a chemical compound derived from toluene-4-sulfonic acid, a strong acid known for its use in acidic catalysis and as a reagent for sulfonate ester formation. The addition of the methanesulfonyl-propyl ester group to the toluene-4-sulfonic acid moiety enhances its solubility and reactivity, making it a crucial intermediate in the synthesis of various organic compounds and pharmaceuticals. Its versatility and high reactivity contribute to its value in the production of a broad spectrum of chemical products.
Uses
Used in Organic Synthesis:
Toluene-4-sulfonic acid 3-Methanesulfonyl-propyl ester is used as a reagent in organic synthesis for its ability to facilitate the formation of various organic compounds. Its enhanced solubility and reactivity make it a preferred choice for reactions involving the synthesis of complex organic molecules.
Used in Pharmaceutical Manufacturing:
In the pharmaceutical industry, toluene-4-sulfonic acid 3-Methanesulfonyl-propyl ester is used as an intermediate in the production of various pharmaceuticals. Its role in the synthesis of active pharmaceutical ingredients (APIs) is significant due to its contribution to the formation of key functional groups and molecular structures necessary for the therapeutic effects of the final drug products.
Used in Acidic Catalysis:
Toluene-4-sulfonic acid 3-Methanesulfonyl-propyl ester is also utilized in acidic catalysis processes, where its strong acidic properties help to speed up chemical reactions by donating protons (H+ ions) to reactants, thereby lowering the activation energy required for the reaction to proceed.
Used in Sulfamate Ester Formation:
As a derivative of toluene-4-sulfonic acid, this compound is used in the formation of sulfamate esters, which are important intermediates in the synthesis of various chemical products, including agrochemicals and pharmaceuticals. The ability to form sulfamate esters expands the range of applications for toluene-4-sulfonic acid 3-Methanesulfonyl-propyl ester in the chemical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 263400-88-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,3,4,0 and 0 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 263400-88:
(8*2)+(7*6)+(6*3)+(5*4)+(4*0)+(3*0)+(2*8)+(1*8)=120
120 % 10 = 0
So 263400-88-0 is a valid CAS Registry Number.
263400-88-0Relevant articles and documents
SYNTHESIS OF 3-({5-CHLORO-1-[3-(METHYLSULFONYL)PROPYL]-1H-INDOL-2 YL} METHYL)-1-(2,2,2-TRIFLUOROETHYL)-1,3-DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE
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, (2021/05/07)
The present invention relates to a chemical synthesis route for preparing the RSV inhibiting compound 3-({5-chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-10 1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, and to new compounds used as intermediate compounds in the multistep process.
SULFONAMIDES AS GPR40- AND GPR120-AGONISTS
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Page/Page column 37-38, (2018/03/06)
The invention relates to compounds acting as agonists of G-protein coupled receptor 120 (GPR120) and/or 40 (GPR40), and having formula (I). Said compounds are useful in the treatment of diseases or disorders modulated by GPR120 and/or GPR40 such as diabet
GPR40 AGONISTS IN ANTI-DIABETIC DRUG COMBINATIONS
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, (2017/10/27)
Disclosed are compositions comprising (a) a GPR40 agonist and (b) an SGLT2 inhibitor, and methods for treating of disorders that are affected by the modulation of the GPR40 receptor and SGLT2 transporter. Such GPR40 compounds are represented by Formula (I) as follows: wherein ring W, R1, R2, R3, R5, R6, A, and Z, are defined herein.
