26346-75-8Relevant academic research and scientific papers
N-heterocyclic carbene-catalyzed formal [3+2] annulation of alkynyl aldehydes with nitrosobenzenes: A highly regioselective umpolung strategy
Han, Runfeng,Qi, Jing,Gu, Jixiang,Ma, Donghui,Xie, Xingang,She, Xuegong
, p. 2705 - 2709 (2014/01/06)
N-Heterocyclic carbene-catalyzed formal [3+2] annulation of alkynyl aldehydes and nitrosobenzenes has been reported. This transformation provided the novel C-X bond formation under mild conditions in moderate to satisfactory yields. The catalytic protocol allows for a rapid construction of 2,5-disubstituted isoxazol-3(2H)-ones and 2,3-disubstituted isoxazol-5(2H)-ones from the same materials via a highly regioselectively umpolung stratgy.
MELDRUM'S ACID IN ORGANIC SYNTHESIS 4. SYNTHESIS OF 5-SUBSTITUTED 2-PHENYLISOXAZOLIN-3-ONES FROM N-ACYLACETYLPHENYLHYDROXYLAMINES
Kunihiko, Mohri,Oikawa, Yuji,Hirao, Ken-ichi,Yonemitsu, Osamu
, p. 521 - 524 (2007/10/02)
When N-acylacetylphenylhydroxylamines, readily prepared from phenylhydroxylamine and acyl Meldrum's acids (5-acyl-2,2-dimethyl-1,3-dioxane-4,6-diones) were refluxed in benzene in the presence of a catalytic amount of p-toluenesulfonic acid, an acid-cataly
