2637-31-2

Usage

Uses

Used in Pharmaceutical Research:
3-(3,4-dihydroquinolin-1(2H)-yl)propan-1-amine is used as a research compound for exploring its potential interactions with the central nervous system. It is being investigated for its possible role in the treatment of neurological disorders and related conditions due to its unique chemical structure and suggested ability to target specific receptors or pathways in the brain.
Used in Drug Development:
In the field of drug development, 3-(3,4-dihydroquinolin-1(2H)-yl)propan-1-amine serves as a lead compound for the design and synthesis of new therapeutic agents. Its potential pharmacological properties make it a valuable candidate for further research and development, with the aim of creating novel treatments for neurological disorders and other related health issues.

InChI:InChI=1/C12H18N2/c13-8-4-10-14-9-3-6-11-5-1-2-7-12(11)14/h1-2,5,7H,3-4,6,8-10,13H2

Upstream product

• 2637-29-8 N-(β-cyanoethyl)-1,2,3,4-tetrahydroquinoline 
• 635-46-1 1,2,3,4-tetrahydroisoquinoline 
• 5003-71-4 3-bromopropylamine hydrochloride 
• 1249583-05-8 1-(3-azidopropyl)-1,2,3,4-tetrahydroquinoline 
• 88014-20-4 3-(1,2,3,4-tetrahydro-1-quinolyl)-1-propanol 
• 89316-70-1 3-(3,4-dihydroquinolin-1(2H)-yl)propyl methanesulfonate 
• 86889-28-3 N-[2-(methoxycarbonyl)ethyl]-1,2,3,4-tetrahydroquinoline 
• 14753-26-5 3-chloropropan-1-amine 

Relevant academic research and scientific papers

Salts of 2- or 3-haloalkylamines in the synthesis of N-aminoalkyl derivatives of heterocyclic and aromatic amines

Reactions of 2-haloethyl- or 3-halopropylamine salts with NH-substrates (indoline, 1,2,3,4-tetrahydroquinoline, aniline, and N-ethylaniline) in the presence of NaHCO3 in water furnished various N-aminoalkyl derivatives of heterocyclic and aromatic amines.

A series of potent crebbp bromodomain ligands reveals an induced-fit pocket stabilized by a cation-π interaction

The benzoxazinone and dihydroquinoxalinone fragments were employed as novel acetyl lysine mimics in the development of CREBBP bromodomain ligands. While the benzoxazinone series showed low affinity for the CREBBP bromodomain, expansion of the dihydroquino

Electrooxidative cyclization of hydroquinolyl alcohols, hydroquinolylamines, and dimethyl aminomalonates

Several hydroquinolyl alcohols and amines were electrochemically oxidized in methanol in the presence of sodium methoxide and potassium iodide to afford the corresponding intramolecular cyclization products. Furthermore, several amino malonates were electrochemically oxidized to yield the corresponding heterocyclic compounds through an intramolecular carbon-carbon bond formation in the presence of sodium cyanide in methanol. CSIRO 2007.