263713-26-4Relevant articles and documents
Effective disruption of phosphoprotein-protein surface interaction using Zn(II) dipicolylamine-based artificial receptors via two-point interaction
Ojida, Akio,Inoue, Masa-Aki,Mito-Oka, Yasuko,Tsutsumi, Hiroshi,Sada, Kazuki,Hamachi, Itaru
, p. 2052 - 2058 (2006)
Protein phosphorylation is ubiquitously involved in living cells, and it is one of the key events controlling protein-protein surface interactions, which are essential in signal transduction cascades. We now report that the small molecular receptors beari
NOVEL CXCR4 ANTAGONIST AND USE THEREOF
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Page/Page column 8-9, (2008/12/08)
The present invention provides a novel CXCR4 antagonist and use thereof. The present invention provides a novel non-peptidic, low-molecular-weight CXCR4 antagonist using various aromatic compounds each containing a dipicolylamine-zinc complex. The present invention also provides use of the novel CXCR4 antagonist as an anti-HIV agent, a metastasis inhibitor for a malignant tumor, or a chronic rheumatoid arthritis treatment and/or prevention agent.