263713-33-3

Basic information

• Product Name: Benzenemethanamine, 4-amino-3-chloro-
• CAS NO: 263713-33-3
• Molecular Formula: C7H9ClN2
• Molecular Weight: 156.615
• Mol File: 263713-33-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, 4-amino-3-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, 4-amino-3-chloro-(263713-33-3)
• EPA Substance Registry System: Benzenemethanamine, 4-amino-3-chloro-(263713-33-3)

Safety Data

• Hazardous Substances Data: 263713-33-3(Hazardous Substances Data)

Upstream product

• 21803-75-8 4-amino-3-chlorobenzonitrile 

Downstream Products

• 911124-39-5 4-Aminomethyl-2-chloro-6-iodophenylamine 
• 799820-72-7 4-amino-3-chlorobenzylamine tert-butyl carbamate 

Relevant articles and documents

TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS

The present invention relates to novel tricyclic compounds that are AKR1C3 dependent KARS inhibitor, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by an AKR1C3 dependent KARS inhibitor.

Aminoacetamide acyl guanidines as beta-secretase inhibitors

There is provided a series of substituted acyl guanidines of Formula (Ik) or a stereoisomer; or a pharmaceutically acceptable salt thereof, wherein R2, R3, R4, R5, R25, R26 and R27 as defined herein, their pharmaceutical compositions and methods of use. These compounds inhibit the processing of amyloid precursor protein (APP) by β-secretase and, more specifically, inhibit the production of Aβ-peptide. The present disclosure is directed to compounds useful in the treatment of neurological disorders related to β-amyloid production, such as Alzheimer's disease and other conditions affected by anti-amyloid activity.

Monoazo and diazo colorants from aminoalkylanilines and bis(aminoalkyl)anilines

Water-insoluble azo dyestuffs of the formula STR1 AND WATER-SOLUBLE ACID ADDITION SALTS THEREOF USEFUL FOR COLORING NATURAL FIBERS, SYNTHETIC FIBER-FORMING MATERIAL AND CELLULOSIC MATERIALS AS WELL AS IN THE MANUFACTURE OF PAPER, VARNISHES, INKS, COATINGS AND PLASTICS IN WHICH A represents an azoic coupling radical derived from a coupling component selected from the group consisting of arylides of hydroxysubstituted carbocyclic aromatic carboxylic acids, 1-aryl-5-hydroxypyrazoles, 6-amino-1-naphthol-3-sulfonic acid, and compounds having an enolizable ketomethylene group of the formula STR2 R is hydrogen, lower-alkyl, lower-alkoxy or halogen; R2 is hydrogen, lower-alkyl, lower-alkoxy, halogen, aminomethyl or 2-aminoethyl with the proviso that A is other than β-naphthol when R2 is aminomethyl or 2-aminoethyl; R1 and R3 are the same or different and are each hydrogen, lower-alkyl, lower-alkoxy, halogen or aminomethyl with the proviso that at least one of R1 and R3 is aminomethyl when R2 is other than aminomethyl or 2-aminoethyl; and n represents an integer whose value is 1 or 2 and corresponds to the number of azo linkages, which dyestuffs are obtained by coupling a diazotized amine of the formula STR3 in which R, R1, R2 and R3 are as defined above with said coupling component.