263841-49-2Relevant academic research and scientific papers
Synthesis and monoamine transporter affinity of front bridged tricyclic 3β-(4′-halo or 4′-methyl)phenyltropanes bearing methylene or carbomethoxymethylene on the bridge to the 2β-position
Zeng, Fanxing,Jarkas, Nachwa,Owens, Michael J.,Kilts, Clinton D.,Nemeroff, Charles B.,Goodman, Mark M.
, p. 4661 - 4663 (2007/10/03)
A series of front bridged tricyclic 3β-(4′-halo or 4′-methyl)phenyltropanes bearing methylene or carbomethoxymethylene on the bridge to the 2β-position was synthesized, and their binding affinities were determined in cells transfected to express human nor
Design, synthesis and biological evaluation of 7-azatricyclodecanes: Analogues of cocaine
Tamiz, Amir P.,Smith, Miles P.,Kozikowski, Alan P.
, p. 297 - 300 (2007/10/03)
The synthesis and biological activity of a series of azatricyclodecane analogues of cocaine are described. All compounds studied in this series exhibit nanomolar potency and good selectivity for the serotonin transporter versus the dopamine transporter. (
