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50373-10-9

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50373-10-9 Usage

General Description

(1R)-TROP-2-ENE-2-CARBOXYLIC ACID METHYL ESTER, also known as trop-2-ene-2-carboxylic acid methyl ester, is a chemical compound that belongs to the class of esters. It is derived from trop-2-ene-2-carboxylic acid, which is a bicyclic organic compound. (1R)-TROP-2-ENE-2-CARBOXYLIC ACID METHYL ESTER is commonly used in organic synthesis and as a building block for the production of various pharmaceuticals and agrochemicals. Its structure and properties make it a versatile compound for use in the preparation of a wide range of organic compounds. This chemical is an important intermediate for the production of various drugs and fine chemicals, making it an important compound in the field of organic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 50373-10-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,3,7 and 3 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 50373-10:
(7*5)+(6*0)+(5*3)+(4*7)+(3*3)+(2*1)+(1*0)=89
89 % 10 = 9
So 50373-10-9 is a valid CAS Registry Number.

50373-10-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl ecgonidine

1.2 Other means of identification

Product number -
Other names Methyl 2-(1-Hydroxy-2-Propanyl)Benzoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:50373-10-9 SDS

50373-10-9Relevant articles and documents

METHOD FOR THE PREPARATION OF N-MONOFLUOROALKYL TROPANES AND THEIR USE

-

Page/Page column 15, (2021/07/31)

The present invention relates to a method for the preparation of an N-monofluoroalkyl tropane, a method for the preparation of a trialkyltin tropane, a method for the preparation of an iodinated and/or radioiodinated tropane and the use of the N-monofluoroalkyl tropane as a precursor in the method for the preparation of the trialkyltin tropane and/or the iodinated and/or radioiodinated tropane.

Synthesis of 3-arylecgonine analogues as inhibitors of cocaine binding and dopamine uptake

Kline Jr.,Wright,Fox,Eldefrawi

, p. 2024 - 2027 (2007/10/02)

3-Arylecgonine analogues were synthesized and characterized by 1H and 13C NMR, IR, and MS. The compounds were synthesized as racemates from cycloheptatriene-7-carboxylic acid or enantiomerically from (-)-cocaine. These analogues were tested for their ability to inhibit [3H]cocaine binding to bovine striatal tissue and to inhibit [3H]dopamine uptake into striatal synaptosomes. Methyl (1RS-2-exo-3-exo)-8-methyl-3-phenyl-8-azabicyclo[3.2.1]octane-2-carboxylate was the most potent analogue. IC50 values for inhibition of cocaine binding and dopamine uptake were 20 and 100 nM, respectively. The racemates and the 1R isomers were equally potent inhibitors of binding and uptake. Methyl (1RS-2-endo-3-exo)-3-(2,4-dinitrophenyl)-8-methyl-8- azabicyclo[3.2.1]octane-2-carboxylate was the least potent. IC50 for inhibition of both binding and uptake was 40 μM.

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