263845-82-5Relevant articles and documents
ANTIMICROBIAL COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT OF INFECTIONS
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Page/Page column 25, (2016/12/22)
The present disclosure provides compositions including a compound (e.g., compounds A-D), pharmaceutical compositions including the compound, methods of treatment of a condition (e.g., an infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents
Huang, Kenneth H.,Veal, James M.,Fadden, R. Patrick,Rice, John W.,Eaves, Jeron,Strachan, Jon-Paul,Barabasz, Amy F.,Foley, Briana E.,Barta, Thomas E.,Ma, Wei,Silinski, Melanie A.,Hu, Mei,Partridge, Jeffrey M.,Scott, Anisa,DuBois, Laura G.,Freed, Tiffany,Steed, Paul M.,Ommen, Andy J.,Smith, Emilie D.,Hughes, Philip F.,Woodward, Angela R.,Hanson, Gunnar J.,McCall, W. Stephen,Markworth, Christopher J.,Hinkley, Lindsay,Jenks, Matthew,Geng, Lifeng,Lewis, Meredith,Otto, James,Pronk, Bert,Verleysen, Katleen,Hall, Steven E.
experimental part, p. 4288 - 4305 (2010/01/16)
A novel class of heat shock protein 90 (Hsp90) inhibitors was developed from an unbiased screen to identify protein targets for a diverse compound library. These indol-4-one and indazol-4-one derived 2-aminobenzamides showed strong binding affinity to Hsp
Cyclohexylamino Benzene, Pyridine, and Pyridazine Derivatives
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Page/Page column 24, (2010/11/28)
Disclosed are compounds and pharmaceutically acceptable salts of Formula (I), wherein Q1, Q2, RN, R1, R2, R5, R6, R7, R8, X1, X2, Xsu