263845-82-5Relevant academic research and scientific papers
ANTIMICROBIAL COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT OF INFECTIONS
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Page/Page column 25, (2016/12/22)
The present disclosure provides compositions including a compound (e.g., compounds A-D), pharmaceutical compositions including the compound, methods of treatment of a condition (e.g., an infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
OMEGA-AMINO ACID DERIVATIVES OF BENZENE, PYRIDINE, AND PYRIDAZINE COMPOUNDS
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Paragraph 0228; 0242; 0243, (2015/12/23)
Disclosed are compounds and pharmaceutically acceptable salts of Formula I wherein R1, R2, R3, R4, R5, R6, R7, n, Q1, Q2, Q3, Y, and X1/sub
Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents
Huang, Kenneth H.,Veal, James M.,Fadden, R. Patrick,Rice, John W.,Eaves, Jeron,Strachan, Jon-Paul,Barabasz, Amy F.,Foley, Briana E.,Barta, Thomas E.,Ma, Wei,Silinski, Melanie A.,Hu, Mei,Partridge, Jeffrey M.,Scott, Anisa,DuBois, Laura G.,Freed, Tiffany,Steed, Paul M.,Ommen, Andy J.,Smith, Emilie D.,Hughes, Philip F.,Woodward, Angela R.,Hanson, Gunnar J.,McCall, W. Stephen,Markworth, Christopher J.,Hinkley, Lindsay,Jenks, Matthew,Geng, Lifeng,Lewis, Meredith,Otto, James,Pronk, Bert,Verleysen, Katleen,Hall, Steven E.
experimental part, p. 4288 - 4305 (2010/01/16)
A novel class of heat shock protein 90 (Hsp90) inhibitors was developed from an unbiased screen to identify protein targets for a diverse compound library. These indol-4-one and indazol-4-one derived 2-aminobenzamides showed strong binding affinity to Hsp
Benzene, Pyridine, and Pyridazine Derivatives
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Page/Page column 45, (2008/12/05)
Disclosed are compounds and pharmaceutically acceptable salts of Formula I wherein A, Q1, Q2, Q3, R31, and R41 are as defined herein. Compounds of Formula I are useful in the treatment of diseases and
Cyclohexylamino Benzene, Pyridine, and Pyridazine Derivatives
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Page/Page column 24, (2010/11/28)
Disclosed are compounds and pharmaceutically acceptable salts of Formula (I), wherein Q1, Q2, RN, R1, R2, R5, R6, R7, R8, X1, X2, Xsu
TETRAHYDROINDOLONE AND TETRAHYDROINDAZOLONE DERIVATIVES
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Page/Page column 83; 84; 96, (2008/06/13)
Disclosed are compounds and pharmaceutically acceptable salts of Formula (I): wherein R1, R2, R3, R4, R5, R6, R7, n, Q1, Q2, Q3, Y, and X1-X4 are as defined
Simplified Synthesis of the Precursor for the Azo Dye Chlorindazone DS
Voss,Eichner
, p. 201 - 204 (2007/10/03)
Recently, Chlorindazone DS 1 has become an important analytical reagent for the detection of gunshot residues from newly introduced ammunition. A simplified synthesis of the precursor of the azo dye 1, 3-amino-6-chloroindazole (2), from commercially available 2,4-dichlorobenzonitrile (3a) has been described. The physical and spectroscopical properties of the known compounds 1 and 2 have been completed. 2-Chloro-4-hydrazinobenzonitrile (4a), 2-bromo-4-hydrazinobenzonitrile (4b) and a new azo dye, 1-(3′-chloro-4′-cyanobenzene-1′-ylazo)-2-hydroxynaphthalene-3, 6-disulfonic acid, disodium salt (5), have been investigated.
