263874-95-9Relevant academic research and scientific papers
Synthesis of peptides with α,β-dehydroamino acids. XIII photoisomerization of Ac-(Z)-ΔpHe-NHMe: Ac-(E)-ΔPhe-NHMe
Kubica, Zbigniew,Kozlecki, Tomasz,Rzeszotarska, Barbara
, p. 296 - 297 (2000)
Easily accessible Ac-(Z)-ΔPhe-NHMe was photoisomerized to so far unknown Ac-(E)-ΔPhe-NHMe. Some parameters of the process leading to a diastereomeric mixture of ratio 90(Z): 10(E) have been tested and the photoisomerization has been carried out on a preparative milligram scale. The isomers were separated via crystallization followed by preparative HPLC.
